This is a unique state of the art review written by a group of 21 international recognized
experts in the field that gathered during a meeting organized by the European Neuromuscular …

Chronic respiratory insufficiency is inevitable in the course of disease progression in patients
with Duchenne muscular dystrophy (DMD). Without mechanical ventilation (MV), morbidity …

… M. Chatwin was funded by a grant from the Jennifer Trust for Spinal Muscular Atrophy,
Stratford-upon-Avon, UK. Support for patient expenses was provided by Brompton Breathers Trust …

Background: Long term non-invasive ventilation (NIV) reduces morbidity and mortality in
patients with neuromuscular and chest wall disease with hypercapnic ventilatory failure, but …

Background Influenza viruses are thought to be spread by droplets, but the role of aerosol
dissemination is unclear and has not been assessed by previous studies. Oxygen therapy, …

INTRODUCTION Clinical context and need for a guideline Neuromuscular diseases as a
group are relatively common with a prevalence of about 1 in 3000. The majority of these …

Background High-flow nasal cannula (HFNC) has become a frequently used noninvasive
form of respiratory support in acute settings; however, evidence supporting its use has only …

… Conflict of interest: M. Chatwin has received lecturing fees on the subject of cough
augmentation from Breas Medical, MPR and Phillips, is a member of Breas clinical advisory board, …

Background There are widely discrepant views on the respiratory management of infants
with spinal muscular atrophy (SMA) type I. Typically, management is palliative. Design A …

Noninvasive ventilatory support (NVS) is sometimes reported as suboptimal in patients with
neuromuscular disease (NMD). The reasons for this include inadequate ventilator settings …