Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development

M Aviram, M Rosenblat - Free Radical Biology and Medicine, 2004 - Elsevier
Paraoxonases PON1 and PON3, which are both associated in serum with HDL, protect the
serum lipids from oxidation, probably as a result of their ability to hydrolyze specific oxidized …

Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans.

M Aviram, L Dornfeld, M Kaplan… - … and clinical Research, 2002 - europepmc.org
The beneficial health effects attributed to the consumption of fruit and vegetables are related,
at least in part, to their antioxidant activity. Of special interest is the inverse relationship …

Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases.

M Aviram - Free Radical Research, 2000 - europepmc.org
Under oxidative stress, which is associated with atherosclerosis, oxidative modifications of
LDL take place. A major effect of antioxidants in the LDL environment is to prevent the …

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

M Aviram, M Rosenblat, CL Bisgaier… - The Journal of …, 1998 - Am Soc Clin Investig
… This later effect can result in PON autoinactivation (M. Aviram, unpublished observation).
H2O2 is a major ROS produced by arterial wall cells during atherogenesis, and it is converted …

[HTML][HTML] Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in …

M Aviram, L Dornfeld, M Rosenblat, N Volkova… - The American journal of …, 2000 - Elsevier
Background: Dietary supplementation with nutrients rich in antioxidants is associated with
inhibition of atherogenic modifications to LDL, macrophage foam cell formation, and …

Comparison of antioxidant potency of commonly consumed polyphenol-rich beverages in the United States

NP Seeram, M Aviram, Y Zhang… - Journal of agricultural …, 2008 - ACS Publications
A number of different beverage products claim to have antioxidant potency due to their
perceived high content of polyphenols. Basic and applied research indicates that pomegranate …

Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL …

M Aviram, M Rosenblat, D Gaitini, S Nitecki, A Hoffman… - Clinical nutrition, 2004 - Elsevier
Dietary supplementation with polyphenolic antioxidants to animals was shown to be associated
with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of …

Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants

M Aviram, M Rosenblat, S Billecke, J Erogul… - Free Radical Biology …, 1999 - Elsevier
… -A column was used with a 0–0.15 M linear gradient of methyl-α-D-mannopyranoside. …
The E 270 for the reaction is 1,310 M −1 cm −1 and one unit of arylesterase activity is equal …

Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and …

M Aviram, E Hardak, J Vaya, S Mahmood, S Milo… - Circulation, 2000 - Am Heart Assoc
… 31 Aviram M. Interaction of oxidized low density lipoprotein with macrophages in atherosclerosis
and the antiatherogenicity of antioxidants. Eur J Clin Chem Clin Biochem.1996; 34:599–…

Consumption of red wine with meals reduces the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation

B Fuhrman, A Lavy, M Aviram - The American journal of clinical nutrition, 1995 - Elsevier
The effect of consumption of red or white wine (11% alcohol) with meals on the propensity
of plasma and low-density lipoprotein (LDL) to undergo lipid peroxidation was studied in 17 …