Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …

This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested, …

Purpose To summarise recommendations about 20 non-surgical interventions for recent
onset (<12 weeks) non-specific low back pain (LBP) and lumbar radiculopathy (LR) based on …

Background: Although second primary cancers are a leading cause of death among men
with testicular cancer, few studies have quantified risks among long-term survivors. Methods: …

With the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a
Strategy, the US National Academy of Sciences, in 2007, precipitated a major change in the …

A novel microRNA (miRNA) quantification method has been developed using stem–loop RT
followed by TaqMan PCR analysis. Stem–loop RT primers are better than conventional …

Background Pembrolizumab is active in head and neck squamous cell carcinoma (HNSCC),
with programmed cell death ligand 1 (PD-L1) expression associated with improved …

Background Postmastectomy radiotherapy is associated with a lower locoregional recurrence
rate and improved disease-free and overall survival when combined with chemotherapy in …

Graphene, a single layer of graphite, has recently attracted considerable attention owing to
its remarkable electronic and structural properties and its possible applications in many …

Over the past five years evidence has mounted that long-duration (>2 s) γ-ray bursts (GRBs)—the
most luminous of all astronomical explosions—signal the collapse of massive stars in …