User profiles for M. M. De Santis

Martina M. De Santis

Institute of Molecular Biotechnology (IMBA), Vienna, Austria
Verified email at imba.oeaw.ac.at
Cited by 948

How to build a lung: latest advances and emerging themes in lung bioengineering

MM De Santis, DA Bölükbas… - European …, 2018 - Eur Respiratory Soc
Chronic respiratory diseases remain a major cause of morbidity and mortality worldwide.
The only option at end-stage disease is lung transplantation, but there are not enough donor …

[HTML][HTML] Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

…, M Khedr, K Kretzschmar, MM De Santis… - Nature …, 2019 - nature.com
… villi and the remaining tissue was cut into 2–3 mm pieces and washed vigorously. This was
then incubated in 2 mM ethylenediaminetetraacetic acid (EDTA) in PBS for 30 min followed …

Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue

MM De Santis, HN Alsafadi, S Tas… - Advanced …, 2021 - Wiley Online Library
… Having confirmed that human rECM bioinks have beneficial rheological and biological
attributes, we tested their ability for 3D bioprinting subsegmental bronchi, which are around 4 mm

Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis

…, HA Baarsma, DE Wagner, MM De Santis… - American journal of …, 2018 - atsjournals.org
De SantisDe Santis … Kneidinger N, Yildirim AO, Callegari J, Takenaka S, Stein MM,
Dumitrascu R, et al. Activation of the WNT/β-catenin pathway attenuates experimental emphysema. …

Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring

…, V Rajendran, MM De Santis, DE Wagner… - Nature cell …, 2018 - nature.com
… Splinting rings were prepared from a 0.5-mm silicone sheet (CWS-S-0.5, Grace Bio-Labs)
by cutting rings with an outer diameter of 12 mm and an inner diameter of 6 mm. After washing …

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β‐catenin activator inducing lung epithelial organoid formation

…, DE Wagner, A Doryab, MM De Santis… - British journal of …, 2021 - Wiley Online Library
Background and Purpose Emphysema is an incurable disease characterized by loss of lung
tissue leading to impaired gas exchange. Wnt/β‐catenin signalling is reduced in …

The preparation of decellularized mouse lung matrix scaffolds for analysis of lung regenerative cell potential

DA Bölükbas, MM De Santis, HN Alsafadi… - Mouse Cell Culture …, 2019 - Springer
… Here we describe and discuss several techniques used for murine lung de- and … 300
μm using a speed of ~1.2 mm/s, a frequency of 100 Hz, and an amplitude of 1 mm [21]. …

Use of short implants (6 mm) in a single‐tooth replacement: A 5‐year follow‐up prospective randomized controlled multicenter clinical study

…, D Botticelli, G Cesaretti, E De Santis… - Clinical Oral …, 2016 - Wiley Online Library
… ‐mm‐long implants supporting single crowns loaded within 7 weeks from installation lose a
small amount of marginal bone during 5 years of functional loading, similar to that of 10‐mm‐…

[HTML][HTML] Microenvironment drug resistance in multiple myeloma: emerging new players

L Di Marzo, V Desantis, AG Solimando, S Ruggieri… - Oncotarget, 2016 - ncbi.nlm.nih.gov
MM cells and BM stromal cells, and contributes to MM pathobiology, inducing MM cell growth,
survival, migration, MM-… on MM cells and is the only integrin able to mediate both MM cell-…

[HTML][HTML] High-risk multiple myeloma: integrated clinical and omics approach dissects the neoplastic clone and the tumor microenvironment

…, P Leone, G Di Lernia, D Giannico, V Desantis… - Journal of clinical …, 2019 - mdpi.com
… The MM microenvironment actively supports the MM disease … impacts MM prognosis due
direct and indirect triggers of MM-… new vessel formation and MM proliferation, irrespective of …