Respiratory muscle dysfunction may develop rapidly in critically ill ventilated patients and is
associated with increased morbidity, length of intensive care unit stay, costs, and mortality. …

Surface electromyography (sEMG) can be used to measure the electrical activity of the
respiratory muscles. The possible applications of sEMG span from patients suffering from acute …

Methods Respiratory mechanics was assessed in COVID-19 patients admitted to the Radboud
University Nijmegen Medical Center as part of standard patient care. Brief occlusions …

Rationale: Controlled mechanical ventilation is used to deliver lung-protective ventilation in
patients with acute respiratory distress syndrome. Despite recognized benefits, such as …

What We Already Know about This Topic Inspiratory muscle weakness delays weaning from
mechanical ventilation, but the contributions of expiratory muscles activity are less well …

Background Physiological dead space (V D /V T ) represents the fraction of ventilation not
participating in gas exchange. In patients with acute respiratory distress syndrome (ARDS), V …

Background Diaphragm dysfunction develops frequently in ventilated intensive care unit (ICU)
patients. Both disuse atrophy (ventilator over-assist) and high respiratory muscle effort (…

Purpose Respiratory muscle weakness frequently develops in critically ill patients and is
associated with adverse outcome, including difficult weaning from mechanical ventilation. Today…

Background High respiratory drive in mechanically ventilated patients with spontaneous
breathing effort may cause excessive lung stress and strain and muscle loading. Therefore, it is …

Background Expiratory muscle weakness leads to difficult ventilator weaning. Maintaining
their activity with functional electrical stimulation (FES) may improve outcome. We studied …