User profiles for Lina Han

Lina Han

MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 3057

2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party

…, ML Guzman, T Haferlach, L Han… - Blood, The Journal …, 2021 - ashpublications.org
Measurable residual disease (MRD) is an important biomarker in acute myeloid leukemia (AML)
that is used for prognostic, predictive, monitoring, and efficacy-response assessments. …

An inhibitor of oxidative phosphorylation exploits cancer vulnerability

…, J Gay, MG Do, J Greer, V Giuliani, J Han, L Han… - Nature medicine, 2018 - nature.com
Metabolic reprograming is an emerging hallmark of tumor biology and an actively pursued
opportunity in discovery of oncology drugs. Extensive efforts have focused on therapeutic …

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia

R Pan, LJ Hogdal, JM Benito, D Bucci, L Han… - Cancer discovery, 2014 - AACR
B-cell leukemia/lymphoma 2 (BCL-2) prevents commitment to programmed cell death at the
mitochondrion. It remains a challenge to identify those tumors that are best treated by …

Improved Activity and SO2 Resistance by Sm-Modulated Redox of MnCeSmTiOx Mesoporous Amorphous Oxides for Low-Temperature NH3-SCR of NO

B Wang, M Wang, L Han, Y Hou, W Bao, C Zhang… - ACS …, 2020 - ACS Publications
The selective catalytic reduction (SCR) technique that converts NO x from the outlet of industrial
boilers at low temperature (<200 C) requires catalysts that possess both the oxidization …

Ionic liquids containing carboxyl acid moieties grafted onto silica: Synthesis and application as heterogeneous catalysts for cycloaddition reactions of epoxide and …

L Han, HJ Choi, SJ Choi, B Liu, DW Park - Green Chemistry, 2011 - pubs.rsc.org
A series of carboxyl-group-functionalized imidazolium-based ionic liquids (CILs) were
synthesized and grafted onto silica gel. The catalytic activity of the resulting heterogeneous …

[HTML][HTML] Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus

…, Z Xie, T Li, S Zhang, C Lai, P Zhu, K Wang, L Han… - Scientific reports, 2016 - nature.com
Respiratory syncytial virus (RSV) infection is a major cause of severe lower respiratory
illness in infants and young children, but the underlying mechanisms responsible for viral …

[HTML][HTML] Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Q Zhang, B Riley-Gillis, L Han, Y Jia, A Lodi… - Signal transduction and …, 2022 - nature.com
Despite high initial response rates, acute myeloid leukemia (AML) treated with the BCL-2–selective
inhibitor venetoclax (VEN) alone or in combinations commonly acquires resistance. …

Silica grafted imidazolium-based ionic liquids: efficient heterogeneous catalysts for chemical fixation of CO 2 to a cyclic carbonate

L Han, SW Park, DW Park - Energy & Environmental Science, 2009 - pubs.rsc.org
Imidazolium-based ionic liquids with varied alkyl chain lengths bearing different anions (Cl−,
Br− and I−) were synthesized and immobilized onto the commercial silica surface (IMIS). …

Diagnostic value of neutrophil gelatinase-associated lipocalin for early diagnosis of cardiac surgery-associated acute kidney injury: a meta-analysis

F Zhou, Q Luo, L Wang, L Han - European Journal of Cardio …, 2016 - academic.oup.com
Neutrophil gelatinase-associated lipocalin (NGAL) has been identified as one of the most
sensitive and specific biomarkers for predicting cardiac surgery-associated acute kidney injury …

Repression of BMI1 in normal and leukemic human CD34+ cells impairs self-renewal and induces apoptosis

A Rizo, S Olthof, L Han, E Vellenga… - Blood, The Journal …, 2009 - ashpublications.org
High expression of BMI1 in acute myeloid leukemia (AML) cells is associated with an unfavorable
prognosis. Therefore, the effects of down-modulation of BMI1 in normal and leukemic …