[HTML][HTML] T2-high asthma phenotypes across lifespan
…, I Ricklefs, G Diekmann, L Liboschik… - European …, 2022 - Eur Respiratory Soc
Rationale In adults, personalised asthma treatment targets patients with type 2 (T2)-high and
eosinophilic asthma phenotypes. It is unclear whether such classification is achievable in …
eosinophilic asthma phenotypes. It is unclear whether such classification is achievable in …
[HTML][HTML] IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction
…, I Ricklefs, G Diekmann, L Liboschik… - European …, 2022 - Eur Respiratory Soc
Background Comprehensive studies investigated the role of T-cells in asthma which led to
personalised treatment options targeting severe eosinophilic asthma. However, little is known …
personalised treatment options targeting severe eosinophilic asthma. However, little is known …
[HTML][HTML] Multicentre feasibility of multiple-breath washout in preschool children with cystic fibrosis and other lung diseases
…, C Stolpe, X Bovermann, L Liboschik… - ERJ Open …, 2020 - Eur Respiratory Soc
Background Multiple-breath washout (MBW)-derived lung clearance index (LCI) detects early
cystic fibrosis (CF) lung disease. LCI was used as an end-point in single- and multicentre …
cystic fibrosis (CF) lung disease. LCI was used as an end-point in single- and multicentre …
Cytokine levels in children and adults with wheezing and asthma show specific patterns of variability over time
M Weckmann, D Thiele, L Liboschik… - Clinical & …, 2021 - academic.oup.com
Levels of cytokines are used for in-depth characterization of patients with asthma; however,
the variability over time might be a critical confounder. To analyze the course of serum …
the variability over time might be a critical confounder. To analyze the course of serum …
[HTML][HTML] Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE cohort
…, I Ricklefs, G Diekmann, L Liboschik… - Journal of Allergy and …, 2023 - Elsevier
Background The Asthma Severity Scoring System (ASSESS) quantifies asthma severity in
adolescents and adults. Scale performance in children younger than 12 years is unknown. …
adolescents and adults. Scale performance in children younger than 12 years is unknown. …
Multicenter feasibility of lung clearance index in preschool children with cystic fibrosis and other lung diseases
…, C Stolpe, R Minso, I Rudolf, N Alfeis, L Liboschick… - 2020 - Eur Respiratory Soc
Background: Early ventilation inhomogeneity in cystic fibrosis (CF) lung disease can be
detected by multiple-breath washout (MBW)-derived lung clearance index (LCI), suggesting this …
detected by multiple-breath washout (MBW)-derived lung clearance index (LCI), suggesting this …
[HTML][HTML] In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma
S Lemmel, M Weckmann, A Wohlers… - Frontiers in …, 2022 - frontiersin.org
… Kopp Johanna Kurz Johanna Kurz Katja Landgraf-Rauf Katja Landgraf-Rauf Kristina
Laubhahn Kristina Laubhahn Lena Liboschik Lena Liboschik Claudia Liebl Claudia Liebl Berrit …
Laubhahn Kristina Laubhahn Lena Liboschik Lena Liboschik Claudia Liebl Claudia Liebl Berrit …
[HTML][HTML] Impact of imposed social isolation and use of face masks on asthma course and mental health in pediatric and adult patients with recurrent wheeze and …
N Maison, H Herbrüggen, B Schaub… - Allergy, Asthma & …, 2021 - Springer
Background There is currently a dramatic increase in the number of COVID-19 cases worldwide,
and further drastic restrictions in our daily life will be necessary to contain this pandemic…
and further drastic restrictions in our daily life will be necessary to contain this pandemic…
17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma
CA Jakwerth, M Weckmann, S Illi… - American journal of …, 2023 - atsjournals.org
Rationale: The strongest genetic risk factor for childhood-onset asthma, the 17q21 locus, is
associated with increased viral susceptibility and disease-promoting processes. Objectives: …
associated with increased viral susceptibility and disease-promoting processes. Objectives: …
Allergen extract‐and component‐based diagnostics in children of the ALLIANCE asthma cohort
C Skevaki, P Tafo, K Eiringhaus… - Clinical & …, 2021 - Wiley Online Library
Background Current in vitro allergen‐specific IgE (sIgE) detection assays measure IgE against
allergen extracts or molecules in a single‐ or multiplex approach. Direct comparisons of …
allergen extracts or molecules in a single‐ or multiplex approach. Direct comparisons of …