[HTML][HTML] miRNA expression profile in human osteosarcoma: role of miR-1 and miR-133b in proliferation and cell cycle control

C Novello, L Pazzaglia… - International …, 2013 - spandidos-publications.com
miRNA profile deregulation affecting downstream signaling pathways activates endpoints
that represent potential biomarkers for prognosis and treatment of tumor patients. In the past …

[PDF][PDF] ZNF687 mutations in severe Paget disease of bone associated with giant cell tumor

…, D Formicola, T Esposito, D Merlotti, L Pazzaglia… - The American Journal of …, 2016 - cell.com
Paget disease of bone (PDB) is a skeletal disorder characterized by focal abnormalities of
bone remodeling, which result in enlarged and deformed bones in one or more regions of the …

NG2/CSPG4–collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion

…, PA Nicolosi, P Braghetta, L Pazzaglia… - Journal of molecular …, 2013 - academic.oup.com
In soft-tissue sarcoma patients, enhanced expression of NG2/CSPG4 proteoglycan in pre-surgical
primary tumours predicts post-surgical metastasis formation and thereby stratifies …

The loss of profilin 1 causes early onset Paget's disease of bone

F Scotto di Carlo, L Pazzaglia… - Journal of Bone and …, 2020 - Wiley Online Library
Paget's disease of bone (PDB) is a late‐onset disorder frequently caused by mutations in the
SQSTM1 gene, leading to hyperactive osteoclasts and resulting in bone pain, deformities, …

[HTML][HTML] Innovative breakthroughs for the treatment of advanced and metastatic synovial sarcoma

L Landuzzi, MC Manara, L Pazzaglia, PL Lollini… - Cancers, 2023 - mdpi.com
Simple Summary Synovial sarcoma (SyS) is a rare malignant soft tissue sarcoma bearing
the chromosomal translocation t(X;18), which encodes the fusion oncoprotein SS18::SSX. …

Differentiating soft tissue leiomyosarcoma and undifferentiated pleomorphic sarcoma: A miRNA analysis

M Guled, L Pazzaglia, I Borze… - Genes …, 2014 - Wiley Online Library
… Mohamed Guled and Laura Pazzaglia contributed equally to … Mohamed Guled and Laura
Pazzaglia contributed equally to … Mohamed Guled and Laura Pazzaglia contributed equally to …

NG2 expression predicts the metastasis formation in soft‐tissue sarcoma patients

MS Benassi, L Pazzaglia, A Chiechi… - Journal of …, 2009 - Wiley Online Library
Enhanced expression levels of NG2 proteoglycan in presurgical original lesions of soft‐tissue
sarcoma (STS) patients defines with 55% probability the immediate (ie, within 12 months …

Identification of markers of possible prognostic value in 57 giant cell tumors of bone

…, P Ragazzini, G Magagnoli, L Pazzaglia… - Oncology …, 2003 - spandidos-publications.com
Giant cell tumor of bone (GCT) is a neoplasm characterized by the presence of large
numbers of multinucleated osteoclast-like giant cells, together with mononuclear spindle-shaped …

[HTML][HTML] Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response?

…, MS Benassi, I Quattrini, L Pazzaglia… - Orphanet journal of rare …, 2015 - Springer
Background Synovial sarcoma (SS) is a rare tumor, with dismal survival when metastatic.
The role of adjuvant chemotherapy is debated. New prognostic and predictive factors are …

[HTML][HTML] p53-dependent activation of microRNA-34a in response to etoposide-induced DNA damage in osteosarcoma cell lines not impaired by dominant negative …

C Novello, L Pazzaglia, A Conti, I Quattrini, S Pollino… - PloS one, 2014 - journals.plos.org
Osteosarcoma (OS) is the most common primary malignant bone tumor and prevalently
occurs in the second decade of life. Etoposide, a chemotherapeutic agent used in combined …