Heart failure (HF) is increasing in prevalence in the United States. Little data exists on race
and gender differences in HF incidence rates and case fatality. The Atherosclerosis Risk in …

Background— Atrial fibrillation (AF) is an important risk factor for stroke and overall mortality,
but information about the preventable burden of AF is lacking. The aim of this study was to …

Spirometric measures of lung function are heritable traits that reflect respiratory health and
predict morbidity and mortality. We meta-analyzed genome-wide association studies for two …

Background— Chronic kidney disease is associated with the incidence of cardiovascular
disease. Chronic kidney disease may also increase the risk of atrial fibrillation (AF), but existing …

Importance The risk of cardiovascular disease (CVD) after infection is poorly understood.
Objective To determine whether hospitalization for pneumonia is associated with an increased …

Reduced kidney function is a risk factor for cardiovascular morbidity and mortality, and both
heart failure (HF) and kidney failure incidences are increasing. This study therefore sought to …

We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Background Type 2 diabetes has been inconsistently associated with the risk of atrial fibrillation
(AF) in previous studies that have frequently been beset by methodological challenges. …

Rationale: Genome-wide association studies (GWAS) have identified loci influencing lung
function, but fewer genes influencing chronic obstructive pulmonary disease (COPD) are …