Simple functional performance tests and mortality in COPD
MA Puhan, L Siebeling, M Zoller… - European …, 2013 - Eur Respiratory Soc
Exercise tests are important to characterise chronic obstructive pulmonary disease patients
and predict their prognosis, but are often not available outside of rehabilitation or research …
and predict their prognosis, but are often not available outside of rehabilitation or research …
[HTML][HTML] Five comorbidities reflected the health status in patients with chronic obstructive pulmonary disease: the newly developed COMCOLD index
A Frei, P Muggensturm, N Putcha, L Siebeling… - Journal of clinical …, 2014 - Elsevier
Objective This study aimed to identify those comorbidities with greatest impact on patient-reported
health status in patients with chronic obstructive pulmonary disease (COPD) and to …
health status in patients with chronic obstructive pulmonary disease (COPD) and to …
No association of 25-hydroxyvitamin D with exacerbations in primary care patients with COPD
Background Cross-sectional studies suggest an association of 25-hydroxyvitamin D with
exacerbations in patients with COPD, but longitudinal evidence from cohort studies is scarce. …
exacerbations in patients with COPD, but longitudinal evidence from cohort studies is scarce. …
Validity and reproducibility of a physical activity questionnaire for older adults: questionnaire versus accelerometer for assessing physical activity in older adults
L Siebeling, S Wiebers, L Beem, MA Puhan… - Clinical …, 2012 - Taylor & Francis
Background Physical activity (PA) is important in older adults for the maintenance of functional
ability. Assessing PA may be difficult. Few PA questionnaires have been compared to …
ability. Assessing PA may be difficult. Few PA questionnaires have been compared to …
The ADO index as a predictor of two-year mortality in general practice-based chronic obstructive pulmonary disease cohorts
…, D Miedinger, S Schafroth Török, A Scherr, L Siebeling… - Respiration, 2014 - karger.com
Background: Existing prediction models for mortality in chronic obstructive pulmonary disease
(COPD) patients have not yet been validated in primary care, which is where the majority …
(COPD) patients have not yet been validated in primary care, which is where the majority …
The inaccuracy of patient recall for COPD exacerbation rate estimation and its implications: results from central adjudication
Background COPD exacerbation incidence rates are often ascertained retrospectively through
patient recall and self-reports. We compared exacerbation ascertainment through patient …
patient recall and self-reports. We compared exacerbation ascertainment through patient …
[HTML][HTML] All that glitters isn't gold: a survey on acknowledgment of limitations in biomedical studies
G Ter Riet, P Chesley, AG Gross, L Siebeling… - PloS one, 2013 - journals.plos.org
Background Acknowledgment of all serious limitations to research evidence is important for
patient care and scientific progress. Formal research on how biomedical authors …
patient care and scientific progress. Formal research on how biomedical authors …
Glycemic memory associated epigenetic changes
AL Siebel, AZ Fernandez, A El-Osta - Biochemical pharmacology, 2010 - Elsevier
It is evident that metabolic memory, whereby diabetic complications continue to develop and
progress in individuals who returned to normal glycemic control after a period of transient …
progress in individuals who returned to normal glycemic control after a period of transient …
[HTML][HTML] HDL and glucose metabolism: current evidence and therapeutic potential
AL Siebel, SE Heywood, BA Kingwell - Frontiers in pharmacology, 2015 - frontiersin.org
High-density lipoprotein (HDL) and its principal apolipoprotein AI (ApoA-I) have now been
convincingly shown to influence glucose metabolism through multiple mechanisms. The key …
convincingly shown to influence glucose metabolism through multiple mechanisms. The key …
[HTML][HTML] ICE COLD ERIC–International collaborative effort on chronic obstructive lung disease: exacerbation risk index cohorts–study protocol for an international …
L Siebeling, G ter Riet, WM Van der Wal… - BMC pulmonary …, 2009 - Springer
Background Chronic Obstructive Pulmonary Disease (COPD) is a systemic disease; morbidity
and mortality due to COPD are on the increase, and it has great impact on patients' lives. …
and mortality due to COPD are on the increase, and it has great impact on patients' lives. …