… [36] The extensive tissue binding of amiodarone results in a pharmacokinetic profile with
a high volume of drug distribution (V d = 5000 L) and an extremely long elimination half-life (t½ …

Although studies show that control of asthma can be achieved in the majority of patients,
surveys repeatedly show that this is not the case in real life. Important measures to implement in …

Idiopathic pulmonary fibrosis (IPF) is a dreadful, chronic, and irreversibly progressive fibrosing
disease leading to death in all patients affected, and IPF acute exacerbations constitute …

… Kolilekas and Manali contributed equally to this work. This work has been supported by the
… Kolilekas has been the primary investigator, participated in clinical and laboratory evaluation …

Introduction Controversy exists about the pathogenesis of idiopathic pulmonary fibrosis acute
exacerbations (IPF-AEs). According to one hypothesis IPF-AEs represent the development …

… Lykourgos Kolilekas and Konstantinos Loverdos contributed equally to this work. … alanine
aminotransferase, 60.5; range, 17-343 IU/L) were noticed in four patients. CRP and ferritin in …

Background Exertional dyspnea is the most prominent and disabling feature in idiopathic
pulmonary fibrosis (IPF). The Medical Research Chronic (MRC) chronic dyspnea score as well …

Background Idiopathic pulmonary fibrosis acute exacerbation (IPF-AE) constitutes IPF’s
most devastating event, representing the unexpected superimposition of diffuse alveolar …

Background and Objective There remains a paucity of large databases for patients with
idiopathic pulmonary fibrosis (IPF) and lung cancer. We aimed to create a European registry. …

The precise definition of a severe asthmatic exacerbation is an issue that presents difficulties.
The term ‘status asthmaticus’ relates severity to outcome and has been used to define a …