[HTML][HTML] The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin

A Ermund, LN Meiss, AM Rodriguez-Pineiro… - Biochemical and …, 2017 - Elsevier
Lane 1 and 2 were loaded with gently scraped mucus from piglet trachea. Protein
standards (St1, St2) with molecular mass (Mr, kDa) of St2. Representative of three repeats. …

The mucus bundles responsible for airway cleaning are retained in cystic fibrosis and by cholinergic stimulation

A Ermund, LN Meiss, B Dolan, A Bähr… - European …, 2018 - Eur Respiratory Soc
The beneficial effect of anticholinergic therapy for chronic lung diseases such as chronic
obstructive pulmonary disease (COPD) is well documented, although cholinergic stimulation …

[HTML][HTML] Granule-stored MUC5B mucins are packed by the non-covalent formation of N-terminal head-to-head tetramers

…, A Ermund, C Ridley, LN Meiss… - Journal of Biological …, 2018 - ASBMB
Most MUC5B mucin polymers in the upper airways of humans and pigs are produced by
submucosal glands. MUC5B forms N-terminal covalent dimers that are further packed into …

OligoG CF‐5/20 normalizes cystic fibrosis mucus by chelating calcium

…, G Skjåk‐Bræk, LN Meiss… - Clinical and …, 2017 - Wiley Online Library
The goal of this study was to determine whether the guluronate (G) rich alginate OligoG CF ‐5/20
(OligoG) could detach cystic fibrosis ( CF ) mucus by calcium chelation, which is also …

[HTML][HTML] Mucus threads from surface goblet cells clear particles from the airways

A Ermund, LN Meiss, B Dolan, F Jaudas… - Respiratory …, 2021 - Springer
Background The mucociliary clearance system driven by beating cilia protects the airways
from inhaled microbes and particles. Large particles are cleared by mucus bundles made in …

Hyper-osmolarity and calcium chelation: Effects on cystic fibrosis mucus

A Ermund, LN Meiss, JK Gustafsson… - European journal of …, 2015 - Elsevier
A non-functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) leads to the
disease cystic fibrosis (CF). Although the CFTR is expressed in multiple organs, pulmonary …

Family planning and reproductive health in cystic fibrosis

LN Meiss, R Jain, TM Kazmerski - Clinics in Chest …, 2022 - chestmed.theclinics.com
Family planning is defined broadly by the World Health Organization (WHO) as the process
that “allows people to attain their desired number of children, if any, and to determine the …

Hypertonic saline releases the attached small intestinal cystic fibrosis mucus

A Ermund, LN Meiss, BJ Scholte… - Clinical and …, 2015 - Wiley Online Library
Hypertonic saline inhalation has become a cornerstone in the treatment of cystic fibrosis (
CF ), but its effect on CF mucus is still not understood. In CF , mucus stagnates in the airways, …

[BOOK][B] Differential dynamical systems

JD Meiss - 2007 - SIAM
… To Don and Peggy Meiss for teaching me to explore, and to Mary Sue Moore for always
believing that I would … The resulting limiting curve has infinite length, and fractal dimension ln 4 …

Class renormalization: Islands around islands

JD Meiss - Physical Review A, 1986 - APS
A ‘‘class’’-c orbit is one that rotates around a periodic orbit of class c-1 with some definite
frequency. This contrasts with the ‘‘level’’of a periodic orbit which is the number of elements in …