Liquid biopsies: donor-derived cell-free DNA for the detection of kidney allograft injury

…, E Schütz, J Beck, J Stegbauer, LC Rump… - Nature Reviews …, 2021 - nature.com
In kidney transplantation, the use of minimally invasive damage biomarkers that are more
sensitive and specific than plasma creatinine will be crucial to enable early, actionable …

International expert consensus statement: percutaneous transluminal renal denervation for the treatment of resistant hypertension

…, KJ Rocha-Singh, LM Ruilope, LC Rump… - Journal of the American …, 2013 - jacc.org
Catheter-based radiofrequency ablation technology to disrupt both efferent and afferent
renal nerves has recently been introduced to clinical medicine after the demonstration of …

Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome—a single-centre experience and review of the literature

…, M Flecken, R Viebahn, LC Rump - Nephrology Dialysis …, 2007 - academic.oup.com
Background. The introduction of sirolimus as an immunosuppressive drug for renal
transplantation has lead to an increase of unexplained interstitial pneumonitis. Methods. Out of a …

[HTML][HTML] Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes

…, E Ritz, LM Ruilope, LC Rump… - … England Journal of …, 2011 - Mass Medical Soc
Background Microalbuminuria is an early predictor of diabetic nephropathy and premature
cardiovascular disease. We investigated whether treatment with an angiotensin-receptor …

Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study

…, MC Brandt, UC Hoppe, O Vonend, LC Rump… - Circulation, 2011 - Am Heart Assoc
Background— Hypertension is associated with impaired glucose metabolism and insulin
resistance. Chronic activation of the sympathetic nervous system may contribute to either …

Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial

…, RE Schmieder, C Ott, A Schmid, M Uder, LC Rump… - The Lancet, 2018 - thelancet.com
Background Early studies suggest that radiofrequency-based renal denervation reduces blood
pressure in patients with moderate hypertension. We investigated whether an alternative …

Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension

…, C Ukena, D Linz, R Schmieder, LC Rump… - …, 2012 - Am Heart Assoc
Increased renal resistive index and urinary albumin excretion are markers of hypertensive
end-organ damage and renal vasoconstriction involving increased sympathetic activity. …

Short-chain fatty acid propionate protects from hypertensive cardiovascular damage

…, A Kushugulova, KU Eckardt, R Dechend, LC Rump… - Circulation, 2019 - Am Heart Assoc
Background: Arterial hypertension and its organ sequelae show characteristics of T cell–mediated
inflammatory diseases. Experimental anti-inflammatory therapies have been shown to …

Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension

…, C Ukena, RE Schmieder, B Cremers, LC Rump… - Circulation, 2013 - Am Heart Assoc
Background— Catheter-based renal sympathetic denervation (RDN) reduces office blood
pressure (BP) in patients with resistant hypertension according to office BP. Less is known …

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled …

…, M Saxena, P Gosse, JP Reilly, T Levy, LC Rump… - The Lancet, 2021 - thelancet.com
Background Endovascular renal denervation reduces blood pressure in patients with mild-to-moderate
hypertension, but its efficacy in patients with true resistant hypertension has not …