EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

E Niżankowska‐Mogilnicka, G Bochenek, L Mastalerz… - Allergy, 2007 - Wiley Online Library
Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) are among the most common
causes of adverse drug reactions. Majority of them are of the hypersensitivity type. The …

Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics

…, G Bochenek, M Kumlin, L Mastalerz… - American journal of …, 1998 - atsjournals.org
… Thus, at the end of the 6 wk, FEV 1 was increased by 0.14 L during the zileuton period
and the mean difference compared with placebo was 0.19 L (95% CI 0.06–0.31; p < 0.01). …

Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma

L Mastalerz, M Setkowicz, M Sanak… - Journal of Allergy and …, 2004 - Elsevier
BACKGROUND: Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can
precipitate adverse reactions in two apparently different clinical conditions: bronchial asthma and …

Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics

…, N Chiang, K Gronert, L Mastalerz… - European …, 2000 - Eur Respiratory Soc
Asthma is characterized by chronic airway inflammation resulting from overproduction of pro-inflammatory
mediators, such as leukotrienes (LT). The authors questioned the biosynthetic …

Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma

M Milewski, L Mastalerz, E Niżankowska… - Journal of allergy and …, 1998 - Elsevier
… recruited to undergo diagnostic NPTs with L-ASA. In 10 of … L-ASA at a total dose of 16 mg
of acetylsalicylic acid applied … and the intensity of response to L-ASA. No systemic reactions…

Increased production of IL-5 and dominant Th2-type response in airways of Churg–Strauss syndrome patients

…, H Plutecka, B Sokolowska, L Mastalerz… - …, 2012 - academic.oup.com
Objective. Churg–Strauss syndrome (CSS) is a rare systemic vasculitis associated with
eosinophilia and asthma. We assessed the local immune response in airways of CSS patients …

[PDF][PDF] Both Th2 and Th17 responses are involved in the pathogenesis of Churg-Strauss syndrome

…, B Sokolowska, H Plutecka, L Mastalerz… - Clinical and …, 2011 - clinexprheumatol.org
Objectives. Churg-Strauss syndrome (CSS) is a rare systemic vasculitis associated with
eosinophilia and granuloma formation. The contribution of in-dividual T-helper cell lineages in …

Protective and bronchodilator effects of prostaglandin E and salbutamol in aspirin-induced asthma.

A Szczeklik, L Mastalerz, E Nizankowska… - American journal of …, 1996 - atsjournals.org
We performed a double-blind, two-phase study on protective and bronchodilator effects of
prostaglandins E2 and E1 (PGE2, PGE1) and salbutamol in patients with aspirin-induced …

Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs

A Zembowicz, L Mastalerz, M Setkowicz… - Archives of …, 2003 - jamanetwork.com
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate various forms of
urticaria by a nonallergic mechanism involving inhibition of cyclooxygenases. Objectives To …

Multimodality assessment of cardiac involvement in Churg-Strauss syndrome patients in clinical remission

W Szczeklik, T Miszalski-Jamka, L Mastalerz… - Circulation …, 2011 - jstage.jst.go.jp
… Pagnoux C, Guillevin L. Cardiac involvement in small and mediumsized vessel vasculitides.
… Churg J, Strauss L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J …