Intestinal organoids and personalized medicine in cystic fibrosis: a successful patient-oriented research collaboration

J Noordhoek, V Gulmans, K van der Ent… - Current opinion in …, 2016 - journals.lww.com
We particularly focus on the importance of patient-oriented research collaborations, and
how such a collaboration helped to develop a personalized medicine approach for CFTR …

[HTML][HTML] Healthy play, better coping: The importance of play for the development of children in health and disease

…, MJNL Benders, RCME Engels, CK van der Ent… - Neuroscience & …, 2018 - Elsevier
Play is of vital importance for the healthy development of children. From a developmental
perspective, play offers ample physical, emotional, cognitive, and social benefits. It allows …

[HTML][HTML] CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials

…, K Conrath, O Van de Steen, K van der Ent - Journal of Cystic …, 2019 - Elsevier
Background Several treatment approaches in cystic fibrosis (CF) aim to correct CF transmembrane
conductance regulator (CFTR) function; the efficacy of each approach is dependent …

[HTML][HTML] Fatigue among children with a chronic disease: a cross-sectional study

…, K van der Ent, MM Van den Heuvel-Eibrink… - BMJ Paediatrics …, 2021 - ncbi.nlm.nih.gov
… *Based on cut-offs as defined in Nap-van der Vlist et al. … The authors also thank Emma
Berkelbach van der Sprenkel, Lotte Meijerink, Pleun Terpstra, Eline Albers, Martine van Grotel …

Exercise oxidative skeletal muscle metabolism in adolescents with cystic fibrosis

…, P Helders, B Arets, K van der Ent… - Experimental …, 2016 - Wiley Online Library
New Findings What is the central question of this study? Do intrinsic abnormalities in oxygenation
and/or muscle oxidative metabolism contribute to exercise intolerance in adolescents …

[HTML][HTML] Preterm birth, infant weight gain, and childhood asthma risk: a meta-analysis of 147,000 European children

…, K Duchen, M Eggesbø, CK van der Ent… - Journal of allergy and …, 2014 - Elsevier
Background Preterm birth, low birth weight, and infant catch-up growth seem associated
with an increased risk of respiratory diseases in later life, but individual studies showed …

[HTML][HTML] Prediction of real-world long-term outcomes of people with CF homozygous for the F508del mutation treated with CFTR modulators

…, P van Mourik, J Kraaijkamp, R van der Meer… - Journal of Personalized …, 2021 - mdpi.com
The clinical response to cystic fibrosis transmembrane conductance regulator (CFTR)
modulators is variable within people with cystic fibrosis (pwCF) homozygous for the F508del …

Early growth characteristics and the risk of reduced lung function and asthma: a meta-analysis of 25,000 children

…, SC Phar, L Craig, G Devereux, CK Van Der Ent… - Journal of allergy and …, 2016 - Elsevier
Background Children born preterm or with a small size for gestational age are at increased
risk for childhood asthma. Objective We sought to assess the hypothesis that these …

[HTML][HTML] Maternal use of probiotics during pregnancy and effects on their offspring's health in an unselected population

…, A Vlieger, G Rijkers, K Van der Ent - European Journal of …, 2016 - Springer
Kors van der Ent has received unrestricted research grants from Grünenthal and
GlaxoSmithKline. The other authors declare that they have no conflicts of interest to disclose. The …

Short-term effect of air stacking and mechanical insufflation–exsufflation on lung function in patients with neuromuscular diseases

…, K van der Ent, W Ludo van der Pol - Chronic Respiratory …, 2022 - journals.sagepub.com
Air stacking (AS) and mechanical insufflation–exsufflation (MI-E) aim to increase cough
efficacy by augmenting inspiratory lung volumes in patients with neuromuscular diseases (NMDs)…