Bmp activity establishes a gradient of positional information throughout the entire neural plate

KA Barth, Y Kishimoto, KB Rohr, C Seydler… - …, 1999 - journals.biologists.com
Bone morphogenetic proteins (Bmps) are key regulators of dorsoventral (DV) patterning.
Within the ectoderm, Bmp activity has been shown to inhibit neural development, promote …

pax2.1 is required for the development of thyroid follicles in zebrafish

…, M Mione, J Favor, M Brand, SW Wilson, KB Rohr - 2002 - journals.biologists.com
The thyroid gland is an organ primarily composed of endoderm-derived follicular cells.
Although disturbed embryonic development of the thyroid gland leads to congenital …

Phenylthiourea disrupts thyroid function in developing zebrafish

OA Elsalini, KB Rohr - Development genes and evolution, 2003 - Springer
Thyroid hormone (T4) can be detected in thyroid follicles in wild-type zebrafish larvae from 3
days of development, when the thyroid has differentiated. In contrast, embryos or larvae …

Analysis of origin and growth of the thyroid gland in zebrafish

…, OA Elsalini, T Wendl, KB Rohr - … dynamics: an official …, 2006 - Wiley Online Library
The zebrafish thyroid gland shows a unique pattern of growth as a differentiated endocrine
gland. Here, we analyze the onset of differentiation, the contribution of lineages, and the …

[PDF][PDF] The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity

KB Rohr, KA Barth, ZM Varga, SW Wilson - Neuron, 2001 - cell.com
The Nodal and Hedgehog signaling pathways influence dorsoventral patterning at all axial
levels of the CNS, but it remains largely unclear how these pathways interact to mediate …

[HTML][HTML] Zebrafish hhex, nk2. 1a, and pax2. 1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors

OA Elsalini, J Von Gartzen, M Cramer, KB Rohr - Developmental Biology, 2003 - Elsevier
During zebrafish development, the thyroid primordium initiates expression of molecular markers
such as hhex and nk2.1a in the endoderm prior to pharynx formation. As expected for an …

Pituitary-interrenal interaction in zebrafish interrenal organ development

TT To, S Hahner, G Nica, KB Rohr… - Molecular …, 2007 - academic.oup.com
To further elucidate pituitary adrenal interactions during development, we studied the
organogenesis of the interrenal organ, the teleost homolog of the mammalian adrenal gland, in …

Arteries define the position of the thyroid gland during its developmental relocalisation

…, S Mundlos, A Grüters, H Krude, KB Rohr - 2006 - journals.biologists.com
During vertebrate development, the thyroid gland undergoes a unique relocalisation from its
site of induction to a distant species-specific position in the cervical mesenchyme. We have …

Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study

…, V Cottin, I Noth, M Selman, KB Rohr… - The Lancet respiratory …, 2019 - thelancet.com
Background A hallmark of idiopathic pulmonary fibrosis is the excess accumulation of
extracellular matrix in the lungs. Degradation of extracellular matrix generates free-circulating …

[HTML][HTML] Expression of nk2. 1a during early development of the thyroid gland in zebrafish

KB Rohr, ML Concha - Mechanisms of development, 2000 - Elsevier
We show here that a zebrafish orthologue of the Thyroid Transcription Factor-1 (TTF-1), nk2.1a,
is expressed in the developing thyroid gland. Using a fate mapping approach we found …