Objective: We sought to assess the incidence, pattern and predictors of occult mediastinal
lymph node involvement (N2) in non-small cell lung cancer patients with negative mediastinal …

The PI3K/AKT/mTOR pathway regulates cell growth and proliferation and is often
dysregulated in cancer due to mutation, amplification, deletion, methylation and post-translational …

Objectives Lung cancer is the most common cause of cancer mortality worldwide and, while
tobacco smoke remains the primary cause, there is increasing concern that vaping and E-…

Fibroblast growth factors (FGFs) regulate a plethora of biological functions, in both the embryonic
and adult stages of development, binding their cognate receptors and thus activating a …

Objective: We sought to assess the clinical implication and prognostic significance of
maximum standardised uptake value (SUV max ) of primary non-small cell lung cancer (NSCLC) …

Background Baicalein is a widely used Chinese herbal medicine derived from Scutellaria
baicalenesis, which has been traditionally used as anti-inflammatory and anti-cancer therapy. …

Thymidine phosphorylase (TP) is a nucleoside metabolism enzyme that plays an important
role in the pyrimidine pathway.TP catalyzes the conversion of thymidine to thymine and 2-…

Early diagnosis and the ability to predict the most relevant treatment option for individuals is
essential to improve clinical outcomes for non-small cell lung cancer (NSCLC) patients. …

Acute renal failure requiring continuous renal replacement therapy post cardiac surgery
carries a high mortality. Most studies have focused on patients with impaired renal function …

BACKGROUND: Despite documented superiority of integrated positron emission
tomography-computerized tomography (PET-CT) over computerized tomography (CT) in lymph node …