European union standards for tuberculosis care

…, R Centis, G Sotgiu, O Menegale, K Kliiman… - 2012 - Eur Respiratory Soc
The European Centre for Disease Prevention and Control (ECDC) and the European
Respiratory Society (ERS) jointly developed European Union Standards for Tuberculosis Care (…

Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study

…, J Ershova, MT Gler, BY Kazennyy, HJ Kim, K Kliiman… - The Lancet, 2012 - thelancet.com
Background The prevalence of extensively drug-resistant (XDR) tuberculosis is increasing
due to the expanded use of second-line drugs in people with multidrug-resistant (MDR) …

Clinical and operational value of the extensively drug-resistant tuberculosis definition

…, G Besozzi, E Girardi, K Kliiman… - European …, 2007 - Eur Respiratory Soc
Currently, no information is available on the effect of resistance/susceptibility to first-line
drugs different from isoniazid and rifampicin in determining the outcome of extensively drug-…

Estimating the future burden of multidrug-resistant and extensively drug-resistant tuberculosis in India, the Philippines, Russia, and South Africa: a mathematical …

…, V Leimane, SN Cho, HJ Kim, K Kliiman… - The Lancet Infectious …, 2017 - thelancet.com
Background Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis
are emerging worldwide. The Green Light Committee initiative supported programmatic …

Sputum culture conversion as a prognostic marker for end-of-treatment outcome in patients with multidrug-resistant tuberculosis: a secondary analysis of data from two …

…, S Keshavjee, HJ Kim, K Kliiman… - The Lancet …, 2015 - thelancet.com
Background Sputum culture conversion is often used as an early microbiological endpoint in
phase 2 clinical trials of tuberculosis treatment on the basis of its assumed predictive value …

Extensive drug resistance acquired during treatment of multidrug-resistant tuberculosis

…, T Kummik, L Kuksa, K Kliiman… - Clinical Infectious …, 2014 - academic.oup.com
Background. Increasing access to drugs for the treatment of multidrug-resistant (MDR)
tuberculosis is crucial but could lead to increasing resistance to these same drugs. In 2000, the …

Multidrug-resistant tuberculosis treatment outcomes in relation to treatment and initial versus acquired second-line drug resistance

…, BY Kazennyy, T Khorosheva, K Kliiman… - Clinical Infectious …, 2016 - academic.oup.com
Background. Resistance to second-line drugs develops during treatment of multidrug-resistant
(MDR) tuberculosis, but the impact on treatment outcome has not been determined. …

TB and MDR/XDR-TB in European Union and European Economic Area countries: managed or mismanaged?

…, S De Lorenzo, G Guenther, K Kliiman… - European …, 2012 - Eur Respiratory Soc
In spite of the growing awareness of emerging drug-resistant Mycobacterium tuberculosis,
the extent of inappropriate tuberculosis (TB) case management may be underestimated, even …

Cost and cost-effectiveness of multidrug-resistant tuberculosis treatment in Estonia and Russia

K Floyd, R Hutubessy, K Kliiman… - European …, 2012 - Eur Respiratory Soc
Evidence on the cost and cost-effectiveness of treatment of multidrug-resistant tuberculosis (MDR-TB)
is limited, and no published data are available from former Soviet Union countries, …

TB and M/XDR-TB infection control in European TB reference centres: the Achilles' heel?

…, S De Lorenzo, G Guenther, K Kliiman… - European …, 2011 - Eur Respiratory Soc
The emergence of multidrug-resistant (MDR) tuberculosis (TB), defined as in vitro resistance
to isoniazid and rifampicin, and extensively drug-resistant (XDR)-TB, defined as in vitro …