Early discharge for patients with exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial

MM Cotton, CE Bucknall, KD Dagg, MK Johnson… - Thorax, 2000 - thorax.bmj.com
BACKGROUND We have previously reported the use of a hospital based respiratory nurse
service (Acute Respiratory Assessment Service, ARAS) to support home treatment of patients …

Vasoconstrictor effects of angiotensin II on the pulmonary vascular bed

BJ Lipworth, KD Dagg - Chest, 1994 - Elsevier
The systemic pressor effects of angiotensin II (ANGII) are well described, whereas relatively
little is known regarding its effects on the pulmonary circulation in humans. Doppler …

Investigations on the renin-angiotensin system in acute severe asthma

SG Ramsay, KD Dagg, IC McKay… - European …, 1997 - Eur Respiratory Soc
The renin-angiotensin system is activated in acute severe asthma. The precise mechanism
of activation is at present unknown, but may involve, beta2-agonists, catecholamines or …

Effect of acute alterations in inspired oxygen tension on methacholine induced bronchoconstriction in patients with asthma.

KD Dagg, LJ Thomson, RA Clayton, SG Ramsay… - Thorax, 1997 - thorax.bmj.com
BACKGROUND: Recent in vitro and in vivo studies in animals have suggested that ambient
oxygen tension may influence airway responsiveness to bronchoconstrictor stimuli. These …

Endothelin-1 levels in induced sputum samples from asthmatic and normal subjects.

GW Chalmers, L Thomson, KJ Macleod, KD Dagg… - Thorax, 1997 - thorax.bmj.com
BACKGROUND: Endothelin-1 (ET-1) is a potent bronchoconstrictor which may have a role in
the pathogenesis of asthma. The levels of ET-1 in saliva, induced sputum, and plasma from …

Effect of angiotensin II on histamine-induced bronchoconstriction in the human airway both in vitro and in vivo

SG Ramsay, RA Clayton, KD Dagg, LJ Thomson… - Respiratory …, 1997 - Elsevier
Effect of angiotensin II on histamine-induced bronchoconstriction in the human airway both
in vitro and in vivo Page 1 RESPIRATORY MEDICINE (1997) 91, 609-615 Effect of …

Comparative effects of angiotensin II on Doppler parameters of left and right heart systolic and diastolic blood flow.

BJ Lipworth, KD Dagg - British journal of clinical pharmacology, 1994 - Wiley Online Library
1. The purpose of the study was to investigate the effects of angiotensin II on Doppler parameters
of right ventricular systolic and diastolic blood flow, and to compare these with effects …

Humoral control of airway tone.

NC Thomson, KD Dagg, SG Ramsay - Thorax, 1996 - ncbi.nlm.nih.gov
The pathways involved in the control of airway tone in man are complex (figure). Airway
smooth muscle can be activated by hormones and vasoactive peptides reaching the lungs from …

The effect of acute alteration in oxygen tension on the bronchodilator response to salbutamol in vitro and in vivo in man

KD Dagg, RA Clayton, LJ Thomson… - Pulmonary …, 2001 - Elsevier
These studies examine the effect of acute hypoxia on airway smooth muscle relaxation in
response to salbutamol in vitro in human isolated bronchi from non-asthmatics and in vivo in-…

A rapid and sensitive method for the determination of the amount of theophylline in blood spots

…, EJ Oliveira, AC Boyter, KD Dagg - Journal of pharmacy …, 2001 - academic.oup.com
Monitoring of drugs (such as theophylline) with a narrow therapeutic window could be
simplified if patients were able to submit blood spots for analysis. This could reduce clinic …