Inhaled corticosteroids for stable chronic obstructive pulmonary disease
…, MS Clarke, EHA Sim, KM Fong - Cochrane Database of …, 2012 - cochranelibrary.com
Background The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary
disease (COPD) has been the subject of much controversy. Major international guidelines …
disease (COPD) has been the subject of much controversy. Major international guidelines …
Respiratory health effects of diesel particulate matter
Particulate matter (PM) emissions involve a complex mixture of solid and liquid particles
suspended in a gas, where it is noted that PM emissions from diesel engines are a major …
suspended in a gas, where it is noted that PM emissions from diesel engines are a major …
Improving lung health in low-income and middle-income countries: from challenges to solutions
Low-income and middle-income countries (LMICs) bear a disproportionately high burden of
the global morbidity and mortality caused by chronic respiratory diseases (CRDs), including …
the global morbidity and mortality caused by chronic respiratory diseases (CRDs), including …
[HTML][HTML] The IASLC lung cancer staging project: proposals for revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung …
The IASLC Staging and Prognostic Factors Committee has collected a new database of
94,708 cases donated from 35 sources in 16 countries around the globe. This has now been …
94,708 cases donated from 35 sources in 16 countries around the globe. This has now been …
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
…, M Suzuki, II Wistuba, KM Fong… - Journal of the …, 2005 - academic.oup.com
Background: Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor
receptor (EGFR) gene in lung cancers are associated with increased sensitivity of these …
receptor (EGFR) gene in lung cancers are associated with increased sensitivity of these …
Aberrant promoter methylation of multiple genes in non-small cell lung cancers
S Zöchbauer-Müller, KM Fong, AK Virmani… - Cancer research, 2001 - AACR
Aberrant methylation of CpG islands acquired in tumor cells in promoter regions is one method
for loss of gene function. We determined the frequency of aberrant promoter methylation (…
for loss of gene function. We determined the frequency of aberrant promoter methylation (…
Somatic Mutations of the HER2 Kinase Domain in Lung Adenocarcinomas
…, K Majmudar, M Suzuki, H Lee, II Wistuba, KM Fong… - Cancer research, 2005 - AACR
Mutations in the epidermal growth factor receptor gene (EGFR) in lung cancers predict for
sensitivity to EGFR kinase inhibitors. HER2 (also known as NEU, EGFR2, or ERBB2) is a …
sensitivity to EGFR kinase inhibitors. HER2 (also known as NEU, EGFR2, or ERBB2) is a …
Molecular damage in the bronchial epithelium of current and former smokers
…, S Lam, J LeRiche, C Behrens, KM Fong… - Journal of the …, 1997 - academic.oup.com
Background: Most lung cancers are attributed to smoking. These cancers have been associated
with multiple genetic alterations and with the presence of preneoplastic bronchial lesions…
with multiple genetic alterations and with the presence of preneoplastic bronchial lesions…
PIK3CA Mutations and Copy Number Gains in Human Lung Cancers
We investigated the frequency and function of mutations and increased copy number of the
PIK3CA gene in lung cancers. PIK3CA mutations are one of the most common gene changes …
PIK3CA gene in lung cancers. PIK3CA mutations are one of the most common gene changes …
[HTML][HTML] The IASLC lung cancer staging project: external validation of the revision of the TNM stage groupings in the eighth edition of the TNM classification of lung …
Introduction Revisions to the TNM stage classifications for lung cancer, informed by the
international database (N = 94,708) of the International Association for the Study of Lung Cancer (…
international database (N = 94,708) of the International Association for the Study of Lung Cancer (…