Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease
…, S Zhou, K Thain, EB Cadogan, J Maltby… - American journal of …, 2012 - atsjournals.org
Rationale: Inflammation and oxidative stress are linked to the deleterious effects of cigarette
smoke in producing chronic obstructive pulmonary disease (COPD). Myeloperoxidase (MPO…
smoke in producing chronic obstructive pulmonary disease (COPD). Myeloperoxidase (MPO…
AZD3293: Pharmacokinetic and pharmacodynamic effects in healthy subjects and patients with Alzheimer's disease
…, N Ye, L Rosen, M Russell, J Maltby… - Journal of …, 2017 - content.iospress.com
AZD3293 (LY3314814) is a promising new potentially disease-modifying BACE1 (β-secretase)
inhibitor in Phase III clinical development for the treatment of Alzheimer’s disease. …
inhibitor in Phase III clinical development for the treatment of Alzheimer’s disease. …
Tolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848
S Delaney, M Biffen, J Maltby, J Bell… - BMJ open …, 2016 - bmjopenrespres.bmj.com
Background Many patients with asthma have a T-helper type 2 (Th2) driven inflammation of
the lung, whereas toll-like receptor 7 (TLR7) agonists, by inducing type I interferons, inhibit …
the lung, whereas toll-like receptor 7 (TLR7) agonists, by inducing type I interferons, inhibit …
E. coli expression and purification of human and cynomolgus IL-15
A Ward, M Anderson, RI Craggs, J Maltby… - Protein expression and …, 2009 - Elsevier
The physiological activities of Interleukin-15 (IL-15) suggest that it could be useful as an
immunomodulator to activate the innate immune system, however, the expression and …
immunomodulator to activate the innate immune system, however, the expression and …
Population pharmacokinetic and pharmacodynamic analysis of plasma Aβ40 and Aβ42 following single oral doses of the BACE1 inhibitor AZD3839 to healthy …
…, T Olsson, J Paraskos, J Maltby… - Clinical …, 2014 - Wiley Online Library
Modulating deposition of Aβ‐containing plaques in the brain may be beneficial in treating
Alzheimer's disease. β‐site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors …
Alzheimer's disease. β‐site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors …
Late intervention with a myeloperoxidase inhibitor prevents emphysema and small airway remodeling in the guinea pig
…, D Sin, E Cadogan, M Soars, S Bolton, J Maltby… - 2011 - Eur Respiratory Soc
Considerable evidence links both inflammation and oxidative stress to the pathogenesis of
COPD. Myeloperoxidase (MPO), a neutrophil product, plays a major role in bacterial killing …
COPD. Myeloperoxidase (MPO), a neutrophil product, plays a major role in bacterial killing …
[PDF][PDF] Introduction: integrating social and environmental archaeologies
J Morris, M Maltby - 2010 - clok.uclan.ac.uk
… The fourth chapter (Maltby) also deals with associated bone groups, but this time from …
Finally, special thanks are due to Justine Biddle for all her hard work in helping to prepare …
Finally, special thanks are due to Justine Biddle for all her hard work in helping to prepare …
Animal 'ritual'killing: from remains to meanings
J Morris - The Ritual Killing and Burial of Animals: European …, 2012 - torrossa.com
… The majority of the dogs interpreted in this way are from Maltby’s investigations of the large
… The reviewer, Ellen Hambleton and Mark Maltby for provided useful comments. Justine …
… The reviewer, Ellen Hambleton and Mark Maltby for provided useful comments. Justine …
[PDF][PDF] Associated bone groups; one archaeologist's rubbish is another's ritual deposition
J Morris - Changing Perspectives on the first millennium BC, 2008 - researchgate.net
… I am indebted to Mark Maltby and Ellen Hambleton for their help, advice, patience and … I
would also like to thank Paul Wheeler and Sarah-Jane Hathaway for their comments, Justine …
would also like to thank Paul Wheeler and Sarah-Jane Hathaway for their comments, Justine …
Animal Biographies in the Iron Age of Wessex: Winnall Down, UK, Revisited
J Morris - The Bioarchaeology of Ritual and Religion, 2017 - torrossa.com
… It should be noted that Maltby would not interpret the animal burials in the same way now;
the original faunal report (Maltby nd) was written in 1981 and the publication in 1985 went to …
the original faunal report (Maltby nd) was written in 1981 and the publication in 1985 went to …