HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

…, DB Goldstein, S John, MR Nelson, J Graham… - Nature …, 2009 - nature.com
Drug-induced liver injury (DILI) is an important cause of serious liver disease. The antimicrobial
agent flucloxacillin is a common cause of DILI, but the genetic basis for susceptibility …

Assessing the survival of transgenic plant DNA in the human gastrointestinal tract

…, AG O'Donnell, S Gockling, J Graham… - Nature …, 2004 - nature.com
The inclusion of genetically modified (GM) plants in the human diet has raised concerns about
the possible transfer of transgenes from GM plants to intestinal microflora and enterocytes…

[HTML][HTML] Meta-analytic evidence for neuroimaging models of depression: state or trait?

J Graham, G Salimi-Khorshidi, C Hagan… - Journal of affective …, 2013 - Elsevier
Background Major Depressive Disorder (MDD) is a leading cause of disease burden
worldwide. With the rapid growth of neuroimaging research on relatively small samples, meta-…

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

PT Donaldson, AK Daly, J Henderson, J Graham… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Co-amoxiclav is one of the most common causes of drug-induced
liver injury (DILI). Although there are previous reports of genetic associations between HLA …

[PDF][PDF] Human stem cell-derived neurons repair circuits and restore neural function

…, T Yuan, Z You, Z Wu, J Xi, A Haberman, J Graham… - Cell Stem Cell, 2021 - cell.com
Although cell transplantation can rescue motor defects in Parkinson's disease (PD) models,
whether and how grafts functionally repair damaged neural circuitry in the adult brain is not …

Epigenetic inactivation of the human sprouty2 (hSPRY2) homologue in prostate cancer

AB McKie, DA Douglas, S Olijslagers, J Graham… - Oncogene, 2005 - nature.com
Abnormal signalling events mediated by receptor tyrosine kinases (RTKs) contribute to
human carcinogenesis. Sprouty2 (Spry2) is a key antagonistic regulator of RTK signalling and …

Outline and surface disruption in animal camouflage

…, IS Winney, A Cantor, J Graham - Proceedings of the …, 2009 - royalsocietypublishing.org
Camouflage is an important strategy in animals to prevent predation. This includes disruptive
coloration, where high-contrast markings placed at an animal's edge break up the true …

Genetic exchange in Bacillus subtilis in soil

JB Graham, CA Istock - Molecular and General Genetics MGG, 1978 - Springer
Genetically labelled strains of Bacillus subtilis have been shown to exchange blocks of
linked genes while growing together in soil. After eight days of incubation, 79% of unselected …

Myositis-specific antibodies identify a distinct interstitial pneumonia with autoimmune features phenotype

J Graham, IB Ventura, CA Newton… - European …, 2020 - Eur Respiratory Soc
Interstitial pneumonia with autoimmune features (IPAF) characterises individuals with
interstitial lung disease (ILD) and features of connective tissue disease (CTD) who fail to satisfy …

Weight loss as a predictor of mortality in patients with interstitial lung disease

J Pugashetti, J Graham, N Boctor… - European …, 2018 - Eur Respiratory Soc
The interstitial lung diseases (ILDs) are a diverse group of diffuse parenchymal lung disorders
that commonly result in pulmonary fibrosis. ILDs are broadly classified according to known …