Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

… Author links open overlay panel Jon R. Konradsen MD, PhD a b c , Takao Fujisawa MD,
PhD d , Marianne van Hage MD, PhD e , Gunilla Hedlin MD, PhD a b c , Christiane Hilger PhD f …

The causes of severe childhood asthma are poorly understood. Our aim was to define global
patterns of gene expression in children with severe therapy-resistant and controlled asthma…

… Author links open overlay panel Jon R. Konradsen MD, PhD a b c ∗ , Anna James PhD c d
∗ , Björn Nordlund RN a b c , Lovisa E. Reinius PhD c e , Cilla Söderhäll PhD e , Erik Melén …

Current data indicate that the “bronchiolitis” diagnosis comprises more than one condition.
Clinically, pathophysiologically, and even genetically three main clusters of patients can be …

Adverse reactions after food intake are commonly reported and a cause of concern and
anxiety that can lead to a very strict diet. The severity of the reaction can vary depending on the …

Background Allergy to cats and dogs and polysensitization towards these animals are
associated with severe childhood asthma. Molecular‐based allergy diagnostics offers new …

Rationale: New approaches are needed to guide personalized treatment of asthma.
Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: …

The clinical presentation of cat and dog allergy vary from discomfort caused by rhinoconjuncitivitis
to severe asthma. Exposure to allergens from these animals is ubiquitous and allergic …

Background Assessment of inflammation is becoming a common practice in the clinical work‐up
of children with persistent asthma. Biomarkers of Th2‐mediated inflammation include …