Pulmonary hypertension is associated with diverse cardiac, pulmonary, and systemic
diseases in neonates, infants, and older children and contributes to significant morbidity and …

Background Inhaled nitric oxide improves gas exchange in neonates, but the efficacy of low-dose
inhaled nitric oxide in reducing the need for extracorporeal membrane oxygenation …

We studied the effects of inhaled nitric oxide (NO) in 9 newborn infants with severe persistent
pulmonary hypertension (PPHN) who were candidates for extracorporeal membrane …

… John P Kinsella, MD John P Kinsella … Correspondence to: John P Kinsella, Division of
Neonatology, The Children's Hospital, Denver, CO 80218, USA …

Background: Although inhaled nitric oxide (iNO) causes selective pulmonary vasodilation
and improves oxygenation in newborn infants with persistent pulmonary hypertension, its …

Background The safety and efficacy of early, low-dose, prolonged therapy with inhaled nitric
oxide in premature newborns with respiratory failure are uncertain. Methods We performed …

Rationale: Pulmonary hypertension (PH) is associated with poor outcomes among preterm
infants with bronchopulmonary dysplasia (BPD), but whether early signs of pulmonary …

OBJECTIVE: To evaluate the safety of intravenous (IV) sildenafil, an inhibitor of cyclic guanosine
monophosphate–specific phosphodiesterase, in treating near-term and term newborns …

Background Inhaled nitric oxide improves oxygenation and lessens the need for
extracorporeal-membrane oxygenation in full-term neonates with hypoxaemic respiratory failure and …

Methods A working group from PPHNet specialists that included neonatologists, cardiologists,
pulmonologists, and intensivists was established to create this document. Although …