Background Comorbidities associated with systemic inflammation including cardiovascular
disease (CVD), stroke and diabetes mellitus (DM) are common among individuals with …

Currently the National Asthma and COPD audit programme (NACAP) only undertakes audit
of COPD primary care in Wales due to its near complete data coverage. We aimed to …

Background Historical data suggest 15% of laboratory animal workers develop IgE sensitisation
and 10% symptoms of laboratory animal allergy (LAA), including occupational asthma. …

Hypersensitivity pneumonitis (HP), or extrinsic allergic alveolitis, is a relatively rare condition
with a variable natural history (acute, subacute, or chronic) and fairly nonspecific features. …

Background The rate at which the prevalence of allergic disease is increasing in many
countries suggests that environmental exposures may be important aetiological factors. …

Exposure to toxic inhalants in the workplace has the potential to cause (in susceptible
individuals) almost any major type of lung disease, such as asthma, COPD and interstitial lung …

Inhalational exposures are increasingly recognized as an important component in the
development of ILDs, and novel exposure-disease associations continue to be discovered. These …

The Global Burden of Disease Study provides a comprehensive assessment of mortality
due to 264 causes in 195 locations from 1980 to 2016. Estimates for the burden of interstitial …

Background The assessment of small airways obstruction (SAO) using spirometry is practiced
in population-based studies. However, it is not clear what are the most used parameters …

Background Small airways obstruction (SAO) is a key feature of both COPD and asthma,
which have been associated with workplace exposures. Whether SAO, which may occur early …