Abstract Treatment of acute lung injury (ALI) and its most severe form, acute respiratory distress
syndrome (ARDS), remain unsolved problems of intensive care medicine. ALI/ARDS are …

Atherosclerosis, a hyperlipidemia-induced chronic inflammatory process of the arterial wall,
develops preferentially at sites where disturbed laminar flow compromises endothelial cell (…

Macrophages in atherosclerotic plaques drive inflammatory responses, degrade lipoproteins,
and phagocytose dead cells. MicroRNAs (miRs) control the differentiation and activity of …

Rationale: Acute lung injury (ALI) causes high mortality, but its molecular mechanisms and
therapeutic options remain ill-defined. Gram-negative bacterial infections are the main cause …

Note: The editorial process for this article was fully handled by Prof. GYH Lip, Editor-in-Chief.

Chemokines mediate monocyte adhesion to dysfunctional endothelial cells (ECs) and
promote arterial inflammation during atherosclerosis. Hypoxia-inducible factor (HIF)-1α is …

Chemokines orchestrate leukocyte trafficking and function in health and disease. Heterophilic
interactions between chemokines in a given microenvironment may amplify, inhibit, or …

Rationale: Chemokine-controlled arterial leukocyte recruitment is a crucial process in
atherosclerosis. Formyl peptide receptor 2 (FPR2) is a chemoattractant receptor that recognizes …

MicroRNAs regulate the maladaptation of endothelial cells (ECs) to naturally occurring
disturbed blood flow at arterial bifurcations resulting in arterial inflammation and atherosclerosis …

Background The total rate as well as the clinical outcome of anastomotic leakage in colorectal
and coloanal anastomosis necessitates a loop stoma for fecal diversion. The aim of this …