Clinical, but not experimental evidence has suggested that air pollution particulate matter (PM)
aggravates myocardial infarction (MI). Here, we aimed to describe mechanisms and …

Rationale Pulmonary fibrosis is a progressive disease with only few treatment options
available at the moment. Recently, the nucleoside uridine has been shown to exert anti-…

Sphingolipids are involved in the pathogenesis of inflammatory diseases. The central molecule
is ceramide, which can be converted into ceramide-1-phosphate (C1P). Although C1P …

Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults, and
remains a difficult to treat disease, especially in elderly patients. AML arises in hematopoietic …

According to the protocol of a three-day acute smoke model, male C57BlL/6 mice (6-8
weeks old) received an intraperitonial (ip) injection of ketamine (10 mg/kg; CP-

Introduction: Extracellular adenosine triphosphate (ATP) via purinergic signalling plays a role
in the development of airway inflammation. Elevated ATP concentration in airway samples …

… Yet, according to Beckert, even their rise was facilitated by shifts in the state’s cotton industry
policies “that they had nothing to do with.”Beckert notices the rise and importance of global …

Leukocyte transmigration through the blood vessel wall is a fundamental step of the
inflammatory response and requires expression of adhesion molecule PECAM-1. Accumulating …

Today, most societies allow more time for young people to transition to adulthood. Compared
to youth from a generation ago, young people today are delaying marriage, prolonging …

… We thank Jessica Beckert, Mariana Klett, and Donata Maciaczyk for technical support. We
also thank Professor Volker Coenen for his continuous support. The Pax6 antibody developed …