BACKGROUND/AIMS: The aim of the study was to determine the prognostic relevance of two
kinases in hepatocellular carcinoma (HCC) important in the regulation of cell proliferation …

The use of left ventricular assist devices in treating patients with end-stage heart failure has
increased significantly in recent years, both as a bridge to transplantation and as destination …

Left ventricular assist devices (LVAD) are used to “bridge” patients with end-stage heart
failure until transplantation of a donor heart can be performed (“bridge to transplantation”). …

Background— Survivin inhibits apoptosis and regulates cell division in many organs, but its
function in the heart is unknown. Methods and Results— We show that cardiac-specific …

Introduction: Folate receptor alpha (FRA) regulates cellular uptake of folates and antifolates.
Information about FRA protein expression in metastatic non–small-cell lung cancer (NSCLC…

MicroRNAs (miRNAs) are a class of small (∼22 nucleotides), non-coding, highly conserved
single-stranded RNAs with posttranscriptional regulatory features, including the regulation …

Background: Lung cancer is the leading cause of cancer-related deaths worldwide. The
typical and atypical carcinoid (TC and AC), the large-cell neuroendocrine carcinoma (LCNEC) …

Background— Whether adult cardiomyocytes have the capacity to regenerate in response
to injury and, if so, to what extent are still issues of intense debate. In human heart failure, …

Background Hypothermic machine perfusion (HMP) for preservation led to compelling success
for outcomes of renal transplantation. Application of different concentrations of oxygen …

The 20S proteasome is almost exclusively localized within cells. High levels of extracellular
proteasomes are also found circulating in the blood plasma of patients suffering from a …