Prone positioning during extracorporeal membrane oxygenation in patients with severe ARDS: the PRONECMO randomized clinical trial
Importance Prone positioning may improve outcomes in patients with severe acute respiratory
distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical …
distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical …
[HTML][HTML] Hydrocortisone plus fludrocortisone for adults with septic shock
…, C Schwebel, C Martin, JF Timsit… - … England Journal of …, 2018 - Mass Medical Soc
Background Septic shock is characterized by dysregulation of the host response to infection,
with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with …
with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with …
[HTML][HTML] Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3 …
…, N Terzi, J Textoris, G Thiery, JF Timsit… - The Lancet infectious …, 2022 - thelancet.com
Background The antiviral efficacy of remdesivir against SARS-CoV-2 is still controversial.
We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with …
We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with …
[HTML][HTML] Clinical and virological data of the first cases of COVID-19 in Europe: a case series
…, X Duval, D Descamps, D Malvy, JF Timsit… - The Lancet Infectious …, 2020 - thelancet.com
Background On Dec 31, 2019, China reported a cluster of cases of pneumonia in people at
Wuhan, Hubei Province. The responsible pathogen is a novel coronavirus, named severe …
Wuhan, Hubei Province. The responsible pathogen is a novel coronavirus, named severe …
Prevalence and outcomes of infection among patients in intensive care units in 2017
Importance Infection is frequent among patients in the intensive care unit (ICU). Contemporary
information about the types of infections, causative pathogens, and outcomes can aid the …
information about the types of infections, causative pathogens, and outcomes can aid the …
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the …
The most recent European guidelines and task force reports on hospital-acquired pneumonia
(HAP) and ventilator-associated pneumonia (VAP) were published almost 10 years ago. …
(HAP) and ventilator-associated pneumonia (VAP) were published almost 10 years ago. …
Central vein catheter-related thrombosis in intensive care patients: incidence, risks factors, and relationship with catheter-related sepsis
Objective To evaluate the incidence and risk factors for catheter-related central vein
thrombosis in ICU patients. Design Observational prospective multicenter study. Setting An 8-bed …
thrombosis in ICU patients. Design Observational prospective multicenter study. Setting An 8-bed …
Continuous versus intermittent infusion of vancomycin in severe staphylococcal infections: prospective multicenter randomized study
…, Y Pean, B Misset, F Thomas, JF Timsit… - Antimicrobial agents …, 2001 - Am Soc Microbiol
A continuous infusion of vancomycin (CIV) may provide an alternative mode of infusion in
severe hospital-acquired methicillin-resistant staphylococcal (MRS) infections. A multicenter, …
severe hospital-acquired methicillin-resistant staphylococcal (MRS) infections. A multicenter, …
[HTML][HTML] Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre …
Background In the Île-de-France region (henceforth termed Greater Paris), extracorporeal
membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) was …
membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) was …
Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled …
Context Use of a chlorhexidine gluconate–impregnated sponge (CHGIS) in intravascular
catheter dressings may reduce catheter-related infections (CRIs). Changing catheter dressings …
catheter dressings may reduce catheter-related infections (CRIs). Changing catheter dressings …