British Thoracic Society guidelines for home oxygen use in adults: accredited by NICE
…, W MacNee, L McDonnell, K Pye, J Suntharalingam… - Thorax, 2015 - thorax.bmj.com
The British Thoracic Society (BTS) Home Oxygen Guideline provides detailed evidence-based
guidance for the use of home oxygen for patients out of hospital. Although the majority of …
guidance for the use of home oxygen for patients out of hospital. Although the majority of …
[HTML][HTML] Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
…, F Soubrier, DF Stein, J Suntharalingam… - Nature …, 2018 - nature.com
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious
variation within components of the transforming growth factor-β pathway, particularly the …
variation within components of the transforming growth factor-β pathway, particularly the …
Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension
J Suntharalingam, CM Treacy, NJ Doughty… - Chest, 2008 - Elsevier
… Author links open overlay panel Jay Suntharalingam MRCP a 1 , Carmen M. Treacy BSc
a , Natalie J. Doughty RN a 2 , Kimberley Goldsmith MD b , Elaine Soon MRCP a , Mark R. …
a , Natalie J. Doughty RN a 2 , Kimberley Goldsmith MD b , Elaine Soon MRCP a , Mark R. …
Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension
…, D Marchesan, J Yang, J Suntharalingam… - American journal of …, 2009 - atsjournals.org
Rationale: Severe pulmonary arterial hypertension (PAH) is characterized by the formation
of plexiform lesions and concentric intimal fibrosis in small pulmonary arteries. The origin of …
of plexiform lesions and concentric intimal fibrosis in small pulmonary arteries. The origin of …
[HTML][HTML] Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis
…, M Simon, O Sitbon, J Suntharalingam… - The lancet respiratory …, 2019 - thelancet.com
Background Rare genetic variants cause pulmonary arterial hypertension, but the contribution
of common genetic variation to disease risk and natural history is poorly characterised. …
of common genetic variation to disease risk and natural history is poorly characterised. …
Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension
…, F Soubrier, L Southgate, J Suntharalingam… - Circulation, 2017 - Am Heart Assoc
Background: Pulmonary arterial hypertension (PAH) is a rare disease with an emerging
genetic basis. Heterozygous mutations in the gene encoding the bone morphogenetic protein …
genetic basis. Heterozygous mutations in the gene encoding the bone morphogenetic protein …
[HTML][HTML] Outcomes of Pseudomonas eradication therapy in patients with non-cystic fibrosis bronchiectasis
…, M Grover, J Rollason, A Malin, J Suntharalingam - Respiratory …, 2012 - Elsevier
Pseudomonas aeruginosa infection is associated with poorer outcomes in non-cystic
fibrosis bronchiectasis. It is unknown whether early eradication improves outcomes. This …
fibrosis bronchiectasis. It is unknown whether early eradication improves outcomes. This …
Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension
…, W Seeger, F Soubrier, J Suntharalingam… - American journal of …, 2020 - atsjournals.org
Rationale: Recently, rare heterozygous mutations in GDF2 were identified in patients with
pulmonary arterial hypertension (PAH). GDF2 encodes the circulating BMP (bone …
pulmonary arterial hypertension (PAH). GDF2 encodes the circulating BMP (bone …
Fibrinogen Aα Thr312Ala polymorphism is associated with chronic thromboembolic pulmonary hypertension
J Suntharalingam, K Goldsmith… - European …, 2008 - Eur Respiratory Soc
Although chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by the
persistence of organised thrombus, few pro-thrombotic risk factors have been identified in …
persistence of organised thrombus, few pro-thrombotic risk factors have been identified in …
Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension
…, F Soubrier, J Suntharalingam… - Circulation: Genomic …, 2018 - Am Heart Assoc
Background: In pulmonary arterial hypertension (PAH), pathological changes in pulmonary
arterioles progressively raise pulmonary artery pressure and increase pulmonary vascular …
arterioles progressively raise pulmonary artery pressure and increase pulmonary vascular …