User profiles for Jahar Bhattacharya

Jahar Bhattacharya

Columbia University
Verified email at cumc.columbia.edu
Cited by 11442

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

…, SK Quadri, S Bhattacharya, J Bhattacharya - Nature medicine, 2012 - nature.com
Bone marrow–derived stromal cells (BMSCs) protect against acute lung injury (ALI). To
determine the role of BMSC mitochondria in this protection, we airway-instilled mice first with …

Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group

…, GA Zimmerman, C Esmon, J Bhattacharya… - American journal of …, 2003 - atsjournals.org
Acute lung injury (ALI) and its more severe form, the acute respiratory distress syndrome (ARDS),
are syndromes of acute respiratory failure that result from acute pulmonary edema and …

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

…, MD Green, G Vunjak-Novakovic, J Bhattacharya… - Nature …, 2014 - nature.com
The ability to generate lung and airway epithelial cells from human pluripotent stem cells (hPSCs)
would have applications in regenerative medicine, modeling of lung disease, drug …

[HTML][HTML] A three-dimensional model of human lung development and disease from pluripotent stem cells

…, M Ciancanelli, JL Casanova, J Bhattacharya… - Nature cell …, 2017 - nature.com
Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three
dimensions (3D) would allow deeper insight into human development, as well as the …

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

…, TS Cohen, AS Prince, J Bhattacharya - Nature, 2014 - nature.com
The tissue-resident macrophages of barrier organs constitute the first line of defence against
pathogens at the systemic interface with the ambient environment. In the lung, resident …

Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

…, S Bhattacharya, J Bhattacharya - Blood, The Journal …, 2009 - ashpublications.org
Mesenchymal stem cells (MSCs), which potentially transdifferentiate into multiple cell types,
are increasingly reported to be beneficial in models of organ system injury. However, the …

Mechanisms regulating endothelial cell barrier function

…, DM Shasby, J Bhattacharya… - … of Physiology-Lung …, 2000 - journals.physiology.org
Endothelium forms a physical barrier that separates blood from tissue. Communication
between blood and tissue occurs through the delivery of molecules and circulating substances …

Regulation and repair of the alveolar-capillary barrier in acute lung injury

J Bhattacharya, MA Matthay - Annual review of physiology, 2013 - annualreviews.org
Considerable progress has been made in understanding the basic mechanisms that regulate
fluid and protein exchange across the endothelial and epithelial barriers of the lung under …

[PDF][PDF] Regulatory T cells promote macrophage efferocytosis during inflammation resolution

…, J Du, J Hook, G Kuriakose, J Bhattacharya… - Immunity, 2018 - cell.com
Regulatory T (Treg) cell responses and apoptotic cell clearance (efferocytosis) represent
critical arms of the inflammation resolution response. We sought to determine whether these …

Mitochondria in lung biology and pathology: more than just a powerhouse

…, CA Piantadosi, J Bhattacharya - … of Physiology-Lung …, 2014 - journals.physiology.org
An explosion of new information about mitochondria reveals that their importance extends
well beyond their time-honored function as the “powerhouse of the cell.” In this Perspectives …