Sex-related differences in cough reflex sensitivity in patients with chronic cough

JA Kastelik, RH Thompson, I Aziz, JC Ojoo… - American journal of …, 2002 - atsjournals.org
Among patients attending specialist cough clinics there is an excess of females, but the
reason for this sex difference is unknown. We tested the hypothesis that the sensitivity of the …

[HTML][HTML] Cough challenge in the assessment of cough reflex

AH Morice, JA Kastelik, R Thompson - British journal of clinical …, 2001 - ncbi.nlm.nih.gov
Cough is the commonest respiratory symptom. Approximately four and a half million consultations
per annum in UK primary care report cough as the main complaint. The use of over-the…

[HTML][HTML] Chronic persistent cough in the community: a questionnaire survey

CF Everett, JA Kastelik, RH Thompson, AH Morice - Cough, 2007 - Springer
Background Chronic cough is a common symptom which causes significant levels of
morbidity. It is becoming increasingly well characterised by research taking place in specialist …

Management of malignant pleural effusion

JA Kastelik - Lung, 2013 - Springer
Malignancy is one of the most common causes of pleural effusion. Malignant pleural effusion
is defined by the presence of malignant cells in the pleural fluid. Development of malignant …

Expression and characterization of the intracellular vanilloid receptor (TRPV1) in bronchi from patients with chronic cough

…, NE New, LR Sadofsky, JA Kastelik… - Experimental lung …, 2005 - Taylor & Francis
TRPV1 is a modulator of noxious stimuli known to be important in the cough reflex. We have
compared the expression of TRPV1 in normal human airways and those from patients with …

Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study

…, AE Stanton, J Holme, JA Kastelik… - European …, 2020 - Eur Respiratory Soc
Background Over 30% of adult patients with pleural infection either die and/or require surgery.
There is no robust means of predicting at baseline presentation which patients will suffer …

Inhaled corticosteroids in chronic obstructive pulmonary disease: a pro–con perspective

KS Babu, JA Kastelik, JB Morjaria - British journal of clinical …, 2014 - Wiley Online Library
Current guidelines limit regular use of inhaled corticosteroids ( ICS ) to a specific subgroup
of patients with chronic obstructive pulmonary disease ( COPD ) in whom the forced …

[HTML][HTML] Management of patients with chronic cough using a clinical protocol: a prospective observational study

…, CF Everett, SA Mulrennan, S Faruqi, JA Kastelik… - Cough, 2013 - Springer
Background and aims Chronic cough is a common symptom the aetiology of which can be
challenging to diagnose. Diagnostic protocols for chronic cough have required the use of …

Palliative care understanding and end‐of‐life decisions in chronic obstructive pulmonary disease

A Fahim, JA Kastelik - The clinical respiratory journal, 2014 - Wiley Online Library
Introduction Chronic obstructive pulmonary disease (COPD) is one of the leading causes of
respiratory morbidity and mortality with limited data on palliative care and evidence of …

Gender differences in airway behaviour

A MORICE, JA KASTELIK, RH THOMPSON - Thorax, 2000 - thorax.bmj.com
I read with interest the article on the eVects of inhaled fluticasone propionate and oral
prednisolone on markers of airway inflammation in asthma recently published in Thorax by Meijer …