Data up to 1995 on the survival of 3-yr cohorts of patients with cystic fibrosis (CF) born in the
UK in the period 1968–1992 have previously been published. The present study reports …

TCL1 is an oncogene activated by recurrent reciprocal translocations at chromosome segment
14q32.1 in the most common of the mature T‐cell malignancies, T‐cell prolymphocytic …

The chaperonin containing TCP-1 (CCT, also known as TRiC) is the only member of the
chaperonin family found in the cytosol of eukaryotes. Like other chaperonins, it assists the …

Chymosin B point mutants, A115T and G243D (chymosin A), were expressed in Escherichia
coli and Trichoderma reesei respectively, characterized biochemically, crystallized and …

Adenosquamous proliferation (ASP), characterised by ductal structures with a dual glandular
and squamous phenotype within desmoplastic stroma, is essentially a hallmark of various …

The loop exchange mutant chymosm 155–164 rhizopuspepsin was expressed in Trichoderma
reesei and exported into the medium to yield a correctly folded and active product. The …

… These were synthesised by the Prague group of Dr J. Sedlacek to extend our earlier work
with them on substitutions at residue III (3). Mutants at the periphery of the active site cleft such …

Low grade adenosquamous carcinoma (LGASC) is a rare form of mammary carcinoma. Only
a handful of reports of this tumour type have been published since Rosen and Ernsberger …

We sought to determine if adenosquamous proliferation of early cellular radial sclerosing
lesions of the breast harbours hot spot mutations and to help clarify its relationship to low‐…

writers of the early eighteenth century. 4 Yet as early as the sixteenth century, it has been
persuasively argued, French legal humanists such as Jaques Cujas and Franvois Hotman were…