Background: Young children have a high incidence of influenza and influenza-related
complications. This study compared the efficacy and safety of cold-adapted influenza vaccine, …

In children, the ratio of forced expiratory volume in 1 s (FEV 1 ) to forced vital capacity (FVC)
is reportedly constant or falls linearly with age, whereas the ratio of residual volume (RV) to …

We describe here a patient with a clinical and molecular diagnosis of recombinase activating
gene 1–deficient (RAG1-deficient) SCID, who produced specific antibodies despite …

Acute liver failure (ALF) in infancy and childhood is a life-threatening emergency. Few conditions
are known to cause recurrent acute liver failure (RALF), and in about 50% of cases, the …

It was recognized by George Boole in the 19th century that classical propositional logic can
be formalized by means of a certain algebraic structure which was later called a Boolean …

The aim of this study was to determine whether outdoor nitrogen dioxide (NO2) was associated
with the prevalence of asthma and respiratory symptoms. In eight nonurban communities…

Cl − secretion in the colon can be activated by an increase of either intracellular Ca 2+ or
cAMP. In this study we examined a possible interdependence of the two second-messenger …

Background Acute liver failure (ALF) in infancy and childhood is a life‐threatening emergency
and in about 50 % the etiology remains unknown. Recently biallelic mutations in NBAS …

We followed a cohort of 1,150 children for 3 yr to investigate long-term effects of ambient
ozone. Nine study sites were selected on the basis of air-quality data to represent a broad …

We used hybrid capture-targeted next-generation sequencing of circulating cell-free DNA (ccfDNA)
of pediatric Hodgkin lymphoma (PHL) patients to determine pathogenic mechanisms …