Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial
J Darenberg, N Ihendyane, J Sjölin… - Clinical infectious …, 2003 - academic.oup.com
The efficacy and safety of high-dose intravenous polyspecific immunoglobulin G (IVIG) as
adjunctive therapy in streptococcal toxic shock syndrome (STSS) were evaluated in a …
adjunctive therapy in streptococcal toxic shock syndrome (STSS) were evaluated in a …
Epidemiology of Severe Streptococcus pyogenes Disease in Europe
TL Lamagni, J Darenberg, B Luca-Harari… - Journal of clinical …, 2008 - Am Soc Microbiol
The past 2 decades have brought worrying increases in severe Streptococcus pyogenes
diseases globally. To investigate and compare the epidemiological patterns of these diseases …
diseases globally. To investigate and compare the epidemiological patterns of these diseases …
Clinical and Microbiological Characteristics of Severe Streptococcus pyogenes Disease in Europe
B Luca-Harari, J Darenberg, S Neal… - Journal of clinical …, 2009 - Am Soc Microbiol
In an attempt to compare the epidemiology of severe Streptococcus pyogenes infection within
Europe, prospective data were collected through the Strep-EURO program. Surveillance …
Europe, prospective data were collected through the Strep-EURO program. Surveillance …
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences
…, DE Low, A McGeer, J Darenberg… - Proceedings of the …, 2014 - National Acad Sciences
We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A
Streptococcus to unravel the nature and timing of molecular events contributing to the emergence, …
Streptococcus to unravel the nature and timing of molecular events contributing to the emergence, …
Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study
A Linnér, J Darenberg, J Sjölin… - Clinical Infectious …, 2014 - academic.oup.com
… In a prospective surveillance study of invasive GAS infections reported by Darenberg et
al [27], 75 STSS cases were identified for which additional clinical and therapeutic …
al [27], 75 STSS cases were identified for which additional clinical and therapeutic …
Intravenous immunoglobulin adjunctive therapy in sepsis, with special emphasis on severe invasive group A streptococcal infections
…, N Ihendyane, J Darenberg - Scandinavian journal of …, 2003 - Taylor & Francis
Immunotherapy targeted against microbial toxins and host mediators has been studied in
many preclinical investigations and clinical trials of sepsis during the past 20 y. Intravenous …
many preclinical investigations and clinical trials of sepsis during the past 20 y. Intravenous …
Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden
J Darenberg, B Luca-Harari, A Jasir… - Clinical infectious …, 2007 - academic.oup.com
Background. The incidence and severity of invasive group A streptococcal infection
demonstrate great variability over time, which at least, in part, seems to be related to group A …
demonstrate great variability over time, which at least, in part, seems to be related to group A …
Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden
I Galanis, A Lindstrand, J Darenberg… - European …, 2016 - Eur Respiratory Soc
The effects of pneumococcal conjugated vaccines (PCVs) need to be investigated. In Stockholm
County, Sweden, PCV7 was introduced in the childhood immunisation programme in …
County, Sweden, PCV7 was introduced in the childhood immunisation programme in …
Comparison of the impact of pneumococcal conjugate vaccine 10 or pneumococcal conjugate vaccine 13 on invasive pneumococcal disease in equivalent …
…, I Galanis, E Morfeldt, J Darenberg… - Clinical Infectious …, 2017 - academic.oup.com
Background Pneumococccal conjugated pneumococcal vaccine (PCV10) and pneumococcal
conjugate vaccine 13 (PCV13), are used in childhood immunization programs worldwide, …
conjugate vaccine 13 (PCV13), are used in childhood immunization programs worldwide, …
Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens: implications for therapy of toxic shock …
J Darenberg, B Söderquist… - Clinical Infectious …, 2004 - academic.oup.com
Administration of intravenous polyspecific immunoglobulin G (IVIG) has been proposed as
adjunctive therapy for toxic shock syndrome caused by Streptococcus pyogenes or …
adjunctive therapy for toxic shock syndrome caused by Streptococcus pyogenes or …