[PDF][PDF] Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
BC Özdemir, T Pentcheva-Hoang, JL Carstens… - Cancer cell, 2014 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) is associated with marked fibrosis and stromal
myofibroblasts, but their functional contribution remains unknown. Transgenic mice with the …
myofibroblasts, but their functional contribution remains unknown. Transgenic mice with the …
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
X Zheng, JL Carstens, J Kim, M Scheible, J Kaye… - Nature, 2015 - nature.com
… and injected cancer cells and helped collect tissue, J.Ki., MS, J.Ka., and C.-CW performed
experiments and collected data. The data was analysed by JLC, VSL, XZ, J.Ki, and C.-CW …
experiments and collected data. The data was analysed by JLC, VSL, XZ, J.Ki, and C.-CW …
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
…, B Tampe, H Sugimoto, K Vadnagara, JL Carstens… - Nature medicine, 2015 - nature.com
Kidney fibrosis is marked by an epithelial-to-mesenchymal transition (EMT) of tubular epithelial
cells (TECs). Here we find that, during renal fibrosis, TECs acquire a partial EMT program …
cells (TECs). Here we find that, during renal fibrosis, TECs acquire a partial EMT program …
Radiographic assessment of progression in osteoarthritis
…, JF Fries, DA Bloch, J Carstens… - … : Official Journal of …, 1987 - Wiley Online Library
We evaluated methods of grading radiologic progression of osteoarthritis (OA). Sets of
radiographs were assessed separately by 8 readers who were blinded to the time sequence. …
radiographs were assessed separately by 8 readers who were blinded to the time sequence. …
[HTML][HTML] Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
The exact nature and dynamics of pancreatic ductal adenocarcinoma (PDAC) immune
composition remains largely unknown. Desmoplasia is suggested to polarize PDAC immunity. …
composition remains largely unknown. Desmoplasia is suggested to polarize PDAC immunity. …
[HTML][HTML] Surface-to-space atmospheric waves from Hunga Tonga–Hunga Ha'apai eruption
The January 2022 Hunga Tonga–Hunga Ha’apai eruption was one of the most explosive
volcanic events of the modern era 1 , 2 , producing a vertical plume that peaked more than 50 …
volcanic events of the modern era 1 , 2 , producing a vertical plume that peaked more than 50 …
Identification of functional heterogeneity of carcinoma-associated fibroblasts with distinct IL6-mediated therapy resistance in pancreatic cancer
PDAC is associated with accumulation of dense stroma consisting of fibroblasts and
extracellular matrix that regulate tumor progression. Here, we identify two distinct populations of …
extracellular matrix that regulate tumor progression. Here, we identify two distinct populations of …
A study of the dynamics of Pd oxidation and PdO reduction by H2and CH4
SC Su, JN Carstens, AT Bell - Journal of Catalysis, 1998 - Elsevier
Palladium is one of the most active catalysts for the catalytic combustion of methane. Since
Pd is oxidized during methane combustion to PdO and PdO is required for high activity, it is of …
Pd is oxidized during methane combustion to PdO and PdO is required for high activity, it is of …
Cyclosporin and tacrolimus impair insulin secretion and transcriptional regulation in INS‐1E beta‐cells
…, J Carstens, KA Jørgensen, J Rungby - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Introducing the calcineurin inhibitors cyclosporin (CsA) and
tacrolimus (Tac) has improved the outcome of organ transplants, but complications such as …
tacrolimus (Tac) has improved the outcome of organ transplants, but complications such as …
Factors Affecting the Catalytic Activity of Pd/ZrO2for the Combustion of Methane
JN Carstens, SC Su, AT Bell - Journal of Catalysis, 1998 - Elsevier
The catalytic combustion of CH 4 has been investigated over Pd/ZrO 2 with the aim of
identifying how the state of oxidation of the Pd affects the catalytic activity, particularly at low …
identifying how the state of oxidation of the Pd affects the catalytic activity, particularly at low …