The relationship between allergic rhinitis and asthma is now established, and most of the
clinical, epidemiological and biological data recommend integrated management. Epithelial …

Increasing evidence of a critical role played by the bronchial epithelium in airway
homeostasis is opening new therapeutic avenues. Its unique situation at the interface with the …

Inconsistent results have been reported regarding IL ‐5 blockade treatment in asthma. There
were no direct between‐treatment comparisons. Only differences between each drug and …

The purpose of this thesis is to investigate new morphological methods for extracting the
characteristics of an image regions. These methods are destined to be applied to image …

Background: Chronic rhinosinusitis is a common comorbidity of asthma. However, sinonasal
involvement in severe steroid-dependent asthma is still undefined. Objective: The aim of the …

The term severe refractory asthma (SRA) in adults applies to patients who remain difficult to
control despite extensive re-evaluation of diagnosis and management following an …

Hitherto, rings have been found exclusively around the four giant planets in the Solar System
1 . Rings are natural laboratories in which to study dynamical processes analogous to …

Haumea—one of the four known trans-Neptunian dwarf planets—is a very elongated and
rapidly rotating body 1 , 2 , 3 . In contrast to other dwarf planets 4 , 5 , 6 , its size, shape, albedo …

Pairs of asteroids sharing similar heliocentric orbits, but not bound together, were found
recently 1 , 2 , 3 . Backward integrations of their orbits indicated that they separated gently with …

The transcription factor nuclear factor–κB (NF-κB) is inactive when bound to its inhibitory
protein IκBα. On cell stimulation with inflammatory signals, IκBα is phosphorylated by IκB …