User profiles for Henrik Knecht
Henrik KnechtVerified email at med2.uni-kiel.de Cited by 2051 |
Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
AE Pérez-Cobas, MJ Gosalbes, A Friedrichs, H Knecht… - Gut, 2013 - gut.bmj.com
Objective Antibiotic (AB) usage strongly affects microbial intestinal metabolism and thereby
impacts human health. Understanding this process and the underlying mechanisms remains …
impacts human health. Understanding this process and the underlying mechanisms remains …
[HTML][HTML] Differential effects of antibiotic therapy on the structure and function of human gut microbiota
AE Pérez-Cobas, A Artacho, H Knecht, ML Ferrus… - PloS one, 2013 - journals.plos.org
The human intestinal microbiota performs many essential functions for the host. Antimicrobial
agents, such as antibiotics (AB), are also known to disturb microbial community equilibrium…
agents, such as antibiotics (AB), are also known to disturb microbial community equilibrium…
[HTML][HTML] Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic …
Amplicon-based next-generation sequencing (NGS) of immunoglobulin (IG) and T-cell
receptor (TR) gene rearrangements for clonality assessment, marker identification and …
receptor (TR) gene rearrangements for clonality assessment, marker identification and …
[HTML][HTML] Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine
Background Antibiotic associated diarrhea and Clostridium difficile infection are frequent
complications of broad spectrum antibiotic therapy. Probiotic bacteria are used as therapeutic …
complications of broad spectrum antibiotic therapy. Probiotic bacteria are used as therapeutic …
ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data
Motivation The study of immunoglobulins and T cell receptors using next-generation
sequencing has finally allowed exploring immune repertoires and responses in their immense …
sequencing has finally allowed exploring immune repertoires and responses in their immense …
Functional consequences of microbial shifts in the human gastrointestinal tract linked to antibiotic treatment and obesity
…, AE Pérez-Cobas, MJ Gosalbes, H Knecht… - Gut …, 2013 - Taylor & Francis
The microbiomes in the gastrointestinal tract (GIT) of individuals receiving antibiotics and
those in obese subjects undergo compositional shifts, the metabolic effects and linkages of …
those in obese subjects undergo compositional shifts, the metabolic effects and linkages of …
[HTML][HTML] Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS
Assessment of clonality, marker identification and measurement of minimal residual disease
(MRD) of immunoglobulin (IG) and T cell receptor (TR) gene rearrangements in lymphoid …
(MRD) of immunoglobulin (IG) and T cell receptor (TR) gene rearrangements in lymphoid …
[HTML][HTML] Effects of β-Lactam Antibiotics and Fluoroquinolones on Human Gut Microbiota in Relation to Clostridium difficile Associated Diarrhea
H Knecht, SC Neulinger, FA Heinsen, C Knecht… - PloS one, 2014 - journals.plos.org
Clostridium difficile infections are an emerging health problem in the modern hospital
environment. Severe alterations of the gut microbiome with loss of resistance to colonization …
environment. Severe alterations of the gut microbiome with loss of resistance to colonization …
Temperature‐driven shifts in the epibiotic bacterial community composition of the brown macroalga Fucus vesiculosus
SB Stratil, SC Neulinger, H Knecht… - …, 2013 - Wiley Online Library
The thallus surface of the brown macroalga F ucus vesiculosus is covered by a specific
biofilm community. This biofilm supposedly plays an important role in the interaction between …
biofilm community. This biofilm supposedly plays an important role in the interaction between …
Dynamic changes of the luminal and mucosa-associated gut microbiota during and after antibiotic therapy with paromomycin
Gut microbiota play a key role in the host's health system. Broad antibiotic therapy is known
to disrupt the microbial balance affecting pathogenic as well as host-associated microbes. …
to disrupt the microbial balance affecting pathogenic as well as host-associated microbes. …