Background Variability of gene expression in human may link gene sequence variability and
phenotypes; however, non-genetic variations, alone or in combination with genetics, may …

Background— We have recently demonstrated that activity of red blood cell glutathione
peroxidase-1 is inversely associated with the risk of cardiovascular events in patients with …

Hereditary angioedema cosegregating with a novel kininogen 1 gene mutation changing the
N-terminal cleavage site of bradykinin Types of hereditary angioedema (HAE) comprise first…

BACKGROUND & AIMS:: Duodenal bicarbonate secretion is in part mediated by an apical
Cl − /HCO 3 − exchanger of unknown molecular nature. The recently discovered dra (down-…

One major expectation from the transcriptome in humans is to characterize the biological basis
of associations identified by genome-wide association studies. So far, few cis expression …

Background— eQTL analyses are important to improve the understanding of genetic association
results. We performed a genome-wide association and global gene expression study to …

Glomerular filtration rate (GFR) declines with age by approx. 1 ml/min/m 2 per year beginning
in the third decade of life. At 70 years of age > 40 ml/min/m 2 of GFR will be lost. Thus, …

Background Attention of the otorhinolaryngologist needs to be drawn to the versatile
aspects of head and neck paragangliomas (PGLs). Methods This study is a retrospective, …

Recently, we showed that ADAMTS13 circulates in an open conformation during the acute
phase of immune-mediated thrombotic thrombocytopenic purpura (iTTP). Although the cause …

Aims Heme oxygenase-1 (HO-1) confers protection to the vasculature and suppresses
inflammatory properties of monocytes and macrophages. It is unclear how HO-1 determines the …