SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

…, NC Kahn, MA Schneider, T Muley, H Winter… - The EMBO …, 2020 - embopress.org
The SARS ‐CoV‐2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID ‐19 …

68Ga-FAPI PET/CT: tracer uptake in 28 different kinds of cancer

…, H Rathke, M Röhrich, H Winter… - Journal of Nuclear …, 2019 - Soc Nuclear Med
The recent development of quinoline-based PET tracers that act as fibroblast-activation-protein
inhibitors (FAPIs) demonstrated promising preclinical and clinical results. FAP is …

Immunological effects of laparoscopic vs open colorectal surgery: a prospective clinical study

MW Wichmann, TP Hüttl, H Winter… - Archives of …, 2005 - jamanetwork.com
Hypothesis Laparoscopy has become a popular approach for the surgical treatment of benign
and even malignant colorectal diseases. Several authors have reported better preserved …

Spatial density and distribution of tumor-associated macrophages predict survival in non–small cell lung carcinoma

…, S Savai Pullamsetti, W Seeger, H Winter… - Cancer research, 2020 - AACR
This study underlines the significance of the density, spatial distribution, and gene
expression of TAM phenotypes as prognostic factors for overall survival in lung cancer. …

[HTML][HTML] Thoracic surgery in the non-intubated spontaneously breathing patient

…, F Eichhorn, W Schmidt, M Kreuter, H Winter - Respiratory …, 2022 - Springer
Background The interest in non-intubated video-assisted thoracic surgery (NIVATS) has
risen over the last decade and numerous terms have been used to describe this technique. …

[HTML][HTML] Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer

…, H Raifer, F Picard, Y Zhang, H Winter… - The Journal of …, 2020 - Am Soc Clin Investig
Immune microenvironment plays a critical role in lung cancer control versus progression
and metastasis. In this investigation, we explored the effect of tumor-infiltrating lymphocyte …

[HTML][HTML] Defining the critical hurdles in cancer immunotherapy

…, P von Hoegen, E Wang, MJP Welters, H Winter… - Journal of translational …, 2011 - Springer
Scientific discoveries that provide strong evidence of antitumor effects in preclinical models
often encounter significant delays before being tested in patients with cancer. While some of …

[HTML][HTML] Predictors of poor outcomes after significant chest trauma in multiply injured patients: a retrospective analysis from the German Trauma Registry (Trauma …

…, P Biberthaler, P Delhey, H Trentzsch, H Winter… - Scandinavian journal of …, 2014 - Springer
Background Blunt thoracic trauma is one of the critical injury mechanisms in multiply injured
trauma victims. Although these patients present a plethora of potential structural damages to …

Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth

…, KP Janssen, M Königshoff, H Winter… - Proceedings of the …, 2017 - National Acad Sciences
IL-22 has been identified as a cancer-promoting cytokine that is secreted by infiltrating immune
cells in several cancer models. We hypothesized that IL-22 regulation would occur at the …

[HTML][HTML] Deep learning for the classification of small-cell and non-small-cell lung cancer

…, G Steinbuss, A Warth, C Zgorzelski, T Muley, H Winter… - Cancers, 2020 - mdpi.com
Reliable entity subtyping is paramount for therapy stratification in lung cancer. Morphological
evaluation remains the basis for entity subtyping and directs the application of additional …