[HTML][HTML] Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

E Snelders, HAL van der Lee, J Kuijpers… - PLoS …, 2008 - journals.plos.org
Background Resistance to triazoles was recently reported in Aspergillus fumigatus isolates
cultured from patients with invasive aspergillosis. The prevalence of azole resistance in A. …

[HTML][HTML] Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus

…, G Schaftenaar, GHJ Kema, HA Van der Lee… - PloS one, 2012 - journals.plos.org
Background Azoles play an important role in the management of Aspergillus diseases.
Azole resistance is an emerging global problem in Aspergillus fumigatus, and may develop …

Voriconazole resistance and mortality in invasive aspergillosis: a multicenter retrospective cohort study

…, B van der Hoven, HA van der Lee… - Clinical Infectious …, 2019 - academic.oup.com
Background Triazole resistance is an increasing problem in invasive aspergillosis (IA).
Small case series show mortality rates of 50%–100% in patients infected with a triazole-resistant …

Aspergillus calidoustus sp. nov., Causative Agent of Human Infections Previously Assigned to Aspergillus ustus

J Varga, J Houbraken, HAL Van Der Lee… - Eukaryotic …, 2008 - Am Soc Microbiol
Aspergillus ustus is a relatively rare human pathogen causing invasive infections in
immunocompromised hosts. In this study isolates originating from clinical and other sources have …

Azole, polyene and echinocandin MIC distributions for wild-type, TR34/L98H and TR46/Y121F/T289A Aspergillus fumigatus isolates in the Netherlands

J van Ingen, HA van der Lee, TAJ Rijs… - Journal of …, 2015 - academic.oup.com
Objectives To determine the MIC distributions of itraconazole, voriconazole and posaconazole
and non-azole drugs for wild-type cyp51A, as well as TR 34 /L98H and TR 46 /Y121F/…

Effects of hydrophobicity on the antifungal activity of α‐helical antimicrobial peptides

Z Jiang, BJ Kullberg, H Van Der Lee… - Chemical biology & …, 2008 - Wiley Online Library
… Hein Van Der Lee… Hein Van Der Lee… Growth of fungi and yeasts was evaluated after 24
h at 30 C by light microscopy and after 48 h by measuring the culture absorbance at 595 nm …

Definitions and measurement of chronic health conditions in childhood: a systematic review

JH Van Der Lee, LB Mokkink, MA Grootenhuis… - Jama, 2007 - jamanetwork.com
ContextChanges in the prevalence of chronic health conditions in childhood have considerable
societal consequences for health care planning and for employment. To obtain valid and …

Prognostic tests in term neonates with hypoxic-ischemic encephalopathy: a systematic review

…, TR de Haan, M Offringa, B Post, JH van der Lee - …, 2013 - publications.aap.org
van Laerhoven, de Haan, van der Lee, and Post acquired the data; and Drs van Laerhoven,
de Haan, and van der Lee … Statistical analyses were performed by Drs van der Lee, de Haan…

Analysis of shared heritability in common disorders of the brain

…, S Seshadri, A Beiser, K Rice, SJ van der Lee… - Science, 2018 - science.org
INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

The intra-and interrater reliability of the action research arm test: a practical test of upper extremity function in patients with stroke

JH Van der Lee, V De Groot, H Beckerman… - Archives of physical …, 2001 - Elsevier
van der Lee JH, de Groot V, Beckerman H, Wagenaar RC, Lankhorst GJ, Bouter LM. The intra-
and interrater reliability of the Action Research Arm test: a practical test of upper extremity …