[HTML][HTML] Withdrawal of inhaled glucocorticoids and exacerbations of COPD

…, H Watz, K Tetzlaff, L Towse, H Finnigan… - … England Journal of …, 2014 - Mass Medical Soc
Background Treatment with inhaled glucocorticoids in combination with long-acting
bronchodilators is recommended in patients with frequent exacerbations of severe chronic …

Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the …

…, P Chanez, R Dahl, B Disse, H Finnigan… - The lancet Respiratory …, 2016 - thelancet.com
Background Blood eosinophil counts might predict response to inhaled corticosteroids (ICS)
in patients with chronic obstructive pulmonary disease (COPD) and a history of …

Continuing education for general practitioners working in rural practice: a review of the literature

S Dowling, J Last, H Finnigan… - Education for Primary …, 2018 - Taylor & Francis
Background Studies demonstrate that the CME/CPD (continuing medical education/continuing
professional development) needs of rural general practitioners (GPs) are unique. Little …

Eosinophilia, frequent exacerbations, and steroid response in chronic obstructive pulmonary disease

…, H Finnigan, G Asijee, C Hallmann, H Watz - American journal of …, 2017 - atsjournals.org
Inhaled corticosteroids (ICSs), together with long-acting bronchodilators, are recommended
for patients with severe chronic obstructive pulmonary disease (COPD) and a history of …

[HTML][HTML] A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma

…, G El Azzi, P Moroni-Zentgraf, H Finnigan… - Journal of Allergy and …, 2017 - Elsevier
Background Studies in adults and adolescents have demonstrated that tiotropium is efficacious
as an add-on therapy to inhaled corticosteroids (ICSs) with or without other maintenance …

[HTML][HTML] Efficacy of BI 671800, an oral CRTH2 antagonist, in poorly controlled asthma as sole controller and in the presence of inhaled corticosteroid treatment

…, K Tetzlaff, MC Nivens, M Sarno, HA Finnigan… - Pulmonary …, 2015 - Elsevier
The prostaglandin D 2 (PGD 2 ) receptor, CRTH2, plays a role in allergic airway inflammation.
The efficacy of BI 671800, a CRTH2 antagonist, was assessed in 2 separate trials in …

[HTML][HTML] Efficacy and safety of vixotrigine in idiopathic or diabetes-associated painful small fibre neuropathy (CONVEY): a phase 2 placebo-controlled enriched …

…, KT Dawson, H Finnigan, A Hajihosseini, H Naik… - …, 2023 - thelancet.com
Background No pharmacological treatments are specifically indicated for painful small fibre
neuropathy (SFN). CONVEY, a phase 2 enriched-enrolment study, evaluated the efficacy …

[HTML][HTML] Stepwise withdrawal of inhaled corticosteroids in COPD patients receiving dual bronchodilation: WISDOM study design and rationale

…, R Dahl, PMA Calverley, L Towse, H Finnigan… - Respiratory …, 2014 - Elsevier
… of this combination, with and without added ICS, should resolve whether a benefit in
preventing exacerbations can still occur when lung function is optimized across the full 24-h day. …

Design of phase 3 studies evaluating vixotrigine for treatment of trigeminal neuralgia

…, WP Cheshire, H Finnigan, K Giblin, H Naik… - Journal of Pain …, 2020 - Taylor & Francis
h Participants taking >1 TN medication at study entry will be required to gradually titrate down
and discontinue their medications so that they are receiving no more than 1 TN medication …

Daily home-based spirometry during withdrawal of inhaled corticosteroid in severe to very severe chronic obstructive pulmonary disease

…, B Disse, H Finnigan, H Magnussen… - … journal of chronic …, 2016 - Taylor & Francis
The WISDOM study (NCT0975195) reported a change in lung function following withdrawal
of fluticasone propionate in patients with severe to very severe COPD treated with tiotropium …