User profiles for Guillermo Tearney

Guillermo Tearney

Massachusetts General Hospital
Verified email at partners.org
Cited by 78369

In vivo endoscopic optical biopsy with optical coherence tomography

GJ Tearney, ME Brezinski, BE Bouma, SA Boppart… - Science, 1997 - science.org
Current medical imaging technologies allow visualization of tissue anatomy in the human
body at resolutions ranging from 100 micrometers to 1 millimeter. These technologies are …

Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography

…, B Cense, BH Park, MC Pierce, GJ Tearney… - Optics letters, 2003 - opg.optica.org
A signal-to-noise ratio (SNR) analysis is presented for optical coherence tomography (OCT)
signals in which time-domain performance is compared with that of the spectral domain. A …

Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working …

GJ Tearney, E Regar, T Akasaka… - Journal of the American …, 2012 - jacc.org
Objectives : The purpose of this document is to make the output of the International Working
Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and …

Characterization of human atherosclerosis by optical coherence tomography

…, M Shishkov, DH Kang, EF Halpern, GJ Tearney - Circulation, 2002 - Am Heart Assoc
Background— High-resolution visualization of atherosclerotic plaque morphology may be
essential for identifying coronary plaques that cause acute coronary events. Optical coherence …

Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound

…, SL Houser, HT Aretz, GJ Tearney - Journal of the American …, 2002 - jacc.org
Objectives : The aim of this study was to evaluate the feasibility and the ability of intravascular
optical coherence tomography (OCT) to visualize the components of coronary plaques in …

High-speed optical frequency-domain imaging

SH Yun, GJ Tearney, JF de Boer, N Iftimia… - Optics express, 2003 - opg.optica.org
We demonstrate high-speed, high-sensitivity, high-resolution optical imaging based on
optical frequency-domain interferometry using a rapidly-tuned wavelength-swept laser. We …

[PDF][PDF] Optical biopsy and imaging using optical coherence tomography

JG Fujimoto, ME Brezinski, GJ Tearney, SA Boppart… - 1995 - researchgate.net
The technology of OCT Optical coherence tomography performs micrometre-scale, cross-sectional
imaging of tissue structure in biological systems by directing a focused beam of light …

In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography

IK Jang, GJ Tearney, B MacNeill, M Takano… - Circulation, 2005 - Am Heart Assoc
Background— The current understanding of the pathophysiology of coronary artery disease
is based largely on postmortem studies. Optical coherence tomography (OCT) is a high-…

Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography

GJ Tearney, H Yabushita, SL Houser, HT Aretz… - Circulation, 2003 - Am Heart Assoc
Background— Macrophage degradation of fibrous cap matrix is an important contributor to
atherosclerotic plaque instability. An imaging technology capable of identifying macrophages …

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

…, H Mou, M Shivaraju, H Bihler, M Mense, GJ Tearney… - Nature, 2018 - nature.com
The airways of the lung are the primary sites of disease in asthma and cystic fibrosis. Here
we study the cellular composition and hierarchy of the mouse tracheal epithelium by single-…