Sleep plays a vital role in brain function and systemic physiology across many body systems.
Problems with sleep are widely prevalent and include deficits in quantity and quality of …

Background: Nonadherence to medication is a recognized problem and may be the most
challenging aspect of treatment. Methods: We performed a systematic review of factors that …

… Medical writing, editorial, and technical support services were provided by Goran Medic of
MAPI Consultancy. Goran Medic did not receive any other form of compensation from Astra …

Purpose In Europe, 4 inhaled antibiotics (tobramycin, colistimethate sodium, aztreonam, and
levofloxacin) are currently approved for the treatment of chronic Pseudomonas aeruginosa …

Background: Clinical decision support (CDS) systems have emerged as tools providing
intelligent decision making to address challenges of critical care. CDS systems can be based on …

Background and Objective: Orphan drugs have been a highlight of discussions due to their
higher prices than non-orphan drugs. There is currently no European consensus on the …

Aim: To assess changes in outcomes and costs upon implementation of continuous vital sign
monitoring in postsurgical patients. Materials & methods: Retrospective analysis of clinical …

Background A challenge in the empiric treatment of complicated urinary tract infection (cUTI)
is identifying the initial appropriate antibiotic therapy (IAAT), which is associated with …

Objectives: To summarize available clinical evidence for cysteamine bitartrate preparations
in the treatment of nephropathic cystinosis as identified through a systematic literature review …

In the absence of head-to-head clinical data, the objective of this study was to indirectly
compare the efficacy and safety of a bivalirudin-based anticoagulation strategy with that of …