User profiles for Glenn D. Crater

Glenn Crater

Clinical Pharma Specialist Consultants, LLC
Verified email at clinicalpharmaspecialist.com
Cited by 2748

[HTML][HTML] Benefits of adding fluticasone propionate/salmeterol to tiotropium in moderate to severe COPD

NA Hanania, GD Crater, AN Morris, AH Emmett… - Respiratory …, 2012 - Elsevier
BACKGROUND: Combining maintenance medications with different mechanisms of action
may improve outcomes in COPD. In this study we evaluated the efficacy and safety of …

Longterm survival among patients with scleroderma-associated pulmonary arterial hypertension treated with intravenous epoprostenol

…, FM Wigley, KM Kral, IH Raphiou, GD Crater - The Journal of …, 2009 - jrheum.org
Objective. Pulmonary arterial hypertension (PAH) remains challenging to treat, especially in
association with scleroderma. We examined survival rates among patients with PAH in …

A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19

…, R Lord, EJ Moran, GD Crater… - European …, 2021 - Eur Respiratory Soc
Severe coronavirus disease 2019 (COVID-19) is characterised by pneumonia with excessive
systemic inflammation, referred to as a “cytokine storm” [1–3]. Dexamethasone treatment …

[HTML][HTML] Effect of fluticasone propionate/salmeterol on arterial stiffness in patients with COPD

…, DB Rubin, AH Emmett, MJ Cicale, GD Crater… - Respiratory …, 2011 - Elsevier
BACKGROUND: COPD is associated with increased arterial stiffness which may in part
explain the cardiovascular morbidity observed in the disease. A causal relationship between …

Effects of CB1R inverse agonist, INV‐202, in patients with features of metabolic syndrome. A randomized, placebo‐controlled, double‐blind phase 1b study

GD Crater, K Lalonde, F Ravenelle… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aims To evaluate the clinical safety, tolerability, and pharmacokinetic and pharmacodynamic
profile of the novel cannabinoid receptor‐1 (CB1R) inverse agonist, INV‐202, in adults with …

[HTML][HTML] Safety, tolerability, pharmacodynamics and pharmacokinetics of umeclidinium and vilanterol alone and in combination: a randomized crossover trial

…, BM Jean-Francois, AF Preece, J Blowers, GD Crater… - PLoS …, 2012 - journals.plos.org
Umeclidinium bromide (GSK573719; UMEC), a new long-acting muscarinic receptor antagonist
(LAMA), is in development with vilanterol (GW642444; VI), a selective long-acting β 2 …

Prevalence of airway obstruction assessed by lung function questionnaire

…, AA Dalal, IH Raphiou, BA Prillaman, GD Crater… - Mayo Clinic …, 2011 - Elsevier
OBJECTIVE To estimate the prevalence of unidentified chronic obstructive pulmonary disease
(COPD) and determine the screening accuracy of the Lung Function Questionnaire (LFQ). …

[HTML][HTML] Fluticasone propionate/salmeterol 250/50 μg versus salmeterol 50 μg after chronic obstructive pulmonary disease exacerbation

JA Ohar, GD Crater, A Emmett, TJ Ferro, AN Morris… - Respiratory …, 2014 - Springer
Background Inhaled long-acting beta 2 agonists used alone and in combination with an
inhaled corticosteroid reduce the risk of exacerbations in patients with stable COPD. However, …

[HTML][HTML] Observational study of the outcomes and costs of initiating maintenance therapies in patients with moderate exacerbations of COPD

…, AO D'Souza, OE Lunacsek, SP Nagar, GD Crater - Respiratory …, 2012 - Springer
Background There are limited data describing patients with moderate COPD exacerbations
and evaluating comparative effectiveness of maintenance treatments in this patient …

[HTML][HTML] Peak inspiratory flows: defining repeatability limits and a predictive equation for different inhalers

…, DA Mahler, JA Ohar, DA Lombardi, GD Crater - Chest, 2020 - Elsevier
Background Peak inspiratory flow (PIF) has been proposed as a measure to assess a patient’s
ability to use dry powder inhalers (DPIs). However, robust quality criteria to determine a …