Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart

…, I Uray, J Lemm, K Youker, GP Noon… - The FASEB …, 2004 - Wiley Online Library
In animal models of lipotoxicity, accumulation of triglycerides within cardiomyocytes is
associated with contractile dysfunction. However, whether intramyocardial lipid deposition is a …

Intra-aortic balloon counterpulsation in cardiogenic shock: report of a cooperative clinical trial

…, M Rubenfire, P Fleming, G Noon… - … England Journal of …, 1973 - Mass Medical Soc
Eighty-seven patients with cardiogenic shock were treated with the intra-aortic counterpulsating
balloon in 10 institutions according to a common protocol. Clinical and physiologic …

Aneurysms of the extracranial carotid artery: twenty-one years' experience

CH McCollum, WG Wheeler, GP Noon… - The American Journal of …, 1979 - Elsevier
Aneurysms of the extracranial carotid artery are an uncommon but potentially serious
problem, usually due to rupture or thromboembolic events. Thirty-seven aneurysms of the …

Decreased expression of tumor necrosis factor-α in failing human myocardium after mechanical circulatory support: a potential mechanism for cardiac recovery

…, RM Delgado, OH Frazier, ML Entman, GP Noon - Circulation, 1999 - Am Heart Assoc
Background—An increasing number of observations in patients with end-stage heart failure
suggest that chronic ventricular unloading by mechanical circulatory support may lead to …

Implantable electrical left ventricular assist systems: Bridge to transplantation and future

…, BP Griffith, WR Frist, DJ Magilligan Jr, GP Noon… - The Annals of thoracic …, 1989 - Elsevier
An implantable left ventricular assist system (LVAS) utilizing an electromechanically driven
dual pusherplate blood pump has been employed in a multiinstitutional trial as a bridge to …

Surgical outcome in 85 patients with primary cardiac tumors

…, R Espada, MK Ramchandani, GP Noon… - The American Journal of …, 2003 - Elsevier
BACKGROUND: We present a large, single institution experience with adult cardiac tumors
and address factors affecting outcome. METHODS: A retrospective review was made of all …

Regression of fibrosis and hypertrophy in failing myocardium following mechanical circulatory support

…, MM Koerner, ME Entman, OH Frazier, GP Noon… - The Journal of heart and …, 2001 - Elsevier
Background: The cellular and structural changes that occur during long-term ventricular
unloading leading to cardiac recovery are poorly understood. However, we have previously …

Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension

…, K Asosingh, W Xu, GP Noon… - American journal of …, 2010 - atsjournals.org
Rationale: Vascular remodeling in pulmonary arterial hypertension (PAH) involves proliferation
and migration of endothelial and smooth muscle cells, leading to obliterative vascular …

Molecular remodelling of dystrophin in patients with end-stage cardiomyopathies and reversal in patients on assistance-device therapy

…, SJ Stetson, A Perez-Verdia, ML Entman, GP Noon… - The lancet, 2002 - thelancet.com
Background Mutations that lead to disruption of cytoskeletal proteins have been recorded in
patients with familial dilated cardiomyopathy. We postulated that changes in cytoskeletal …

Development and clinical application of the MicroMed DeBakey VAD

GP Noon, D Morley, S Irwin… - Current opinion in …, 2000 - journals.lww.com
A miniaturized axial flow pump to provide left ventricular assistance has been developed.
Such a device has the potential to address limitations of the larger pulsatile devices. Clinical …