In obese people, the presence of adipose tissue around the rib cage and abdomen and in
the visceral cavity loads the chest wall and reduces functional residual capacity (FRC). The …

Excessive airway obstruction is the cause of symptoms and abnormal lung function in asthma.
As airway smooth muscle (ASM) is the effecter controlling airway calibre, it is suspected …

… King and colleagues 5 reported an automated CT image analysis algorithm (CT airway
morphometry) to measure Ai, Aaw, and airway angle of orientation. In this method, luminal area …

Inert gas washout tests, performed using the single- or multiple-breath washout technique,
were first described over 60 years ago. As measures of ventilation distribution inhomogeneity, …

… This task force was initiated by its two co-chairs Gregory King and Ellie Oostveen, who
developed the aims and outline of the document and brought together the members of the task …

Background Increased airway smooth muscle bulk is a pathological feature of asthma.
Asthma is well controlled by the combined inhalation of glucocorticoids and β 2 -adrenoceptor …

… Gregory King has received travel sponsorship from GlaxoSmithKline to attend the ATS ASM
… A proportion of Dr King’s research work is conducted at the Woolcock Institute of Medical …

Increased wheeze and asthma diagnosis in obesity may be due to reduced lung volume
with subsequent airway narrowing. Asthma (wheeze and airway hyperresponsiveness), …

Background Increased proliferation of bronchial smooth-muscle cells may lead to increased
muscle mass in the airways of patients with asthma. The antiproliferative effect of …

Recently, “Technical standards for respiratory oscillometry” was published, which reviewed
the physiological basis of oscillometric measures and detailed the technical factors related to …