User profiles for G. Ruiter
Graham de RuiterAssistant Professor of Chemistry, Technion - Israel Institute of Technology Verified email at technion.ac.il Cited by 1445 |
The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis
M Verheij, GA Ruiter, SF Zerp… - Radiotherapy and …, 1998 - Elsevier
Ionizing radiation, like a variety of other cellular stress factors, initiates apoptosis, or
programmed cell death, in many cell systems. This mode of radiation-induced cell kill should be …
programmed cell death, in many cell systems. This mode of radiation-induced cell kill should be …
Dysregulated renin–angiotensin–aldosterone system contributes to pulmonary arterial hypertension
…, L Tu, ML Handoko, S Rain, G Ruiter… - American journal of …, 2012 - atsjournals.org
Rationale: Patients with idiopathic pulmonary arterial hypertension (iPAH) often have a low
cardiac output. To compensate, neurohormonal systems such as the renin–angiotensin–…
cardiac output. To compensate, neurohormonal systems such as the renin–angiotensin–…
Iron deficiency is common in idiopathic pulmonary arterial hypertension
G Ruiter, S Lankhorst, A Boonstra… - European …, 2011 - Eur Respiratory Soc
The aims of this study were to assess the prevalence of iron deficiency in idiopathic pulmonary
arterial hypertension (IPAH) and investigate whether oral iron supplementation has …
arterial hypertension (IPAH) and investigate whether oral iron supplementation has …
Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase–Akt/PKB survival pathway
GA Ruiter, SF Zerp, H Bartelink… - Anti-cancer …, 2003 - journals.lww.com
Synthetic alkyl-lysophospholipids (ALPs) represent a new class of anti-tumor agents that
target cell membranes and induce apoptosis. However, the exact mechanisms by which ALPs …
target cell membranes and induce apoptosis. However, the exact mechanisms by which ALPs …
Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis
GA Ruiter, M Verheij, SF Zerp… - International Journal of …, 2001 - Elsevier
Synthetic alkyl-lysophospholipids (ALPs, also referred to as ether-phospholipids) have been
studied as antitumor agents for more than a decade. Classical examples of these ALPs …
studied as antitumor agents for more than a decade. Classical examples of these ALPs …
Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis
GA Ruiter, SF Zerp, H Bartelink, WJ van Blitterswijk… - Cancer research, 1999 - AACR
Alkyl-lysophospholipids (ALPs) represent a new class of antitumor drugs that induce apoptotic
cell death in a variety of tumor cell lines. Although their precise mechanism of action is …
cell death in a variety of tumor cell lines. Although their precise mechanism of action is …
Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency
G Ruiter, E Manders, CM Happé, I Schalij… - Pulmonary …, 2015 - journals.sagepub.com
… In addition, LV and RV free wall mass index remained stable (LV: 59 ± 15 g/m 2 before vs.
62 ± 17 g/m 2 after; RV: 51 ± 29 g/m 2 before vs. 56 ± 31 g/m 2 after; both NS; Table S4). …
62 ± 17 g/m 2 after; RV: 51 ± 29 g/m 2 before vs. 56 ± 31 g/m 2 after; both NS; Table S4). …
Right ventricular failure in idiopathic pulmonary arterial hypertension is associated with inefficient myocardial oxygen utilization
YY Wong, G Ruiter, M Lubberink… - Circulation: Heart …, 2011 - Am Heart Assoc
Background— In idiopathic pulmonary arterial hypertension (IPAH), increased right ventricular
(RV) power is required to maintain cardiac output. For this, RV O 2 consumption (MVO 2 ) …
(RV) power is required to maintain cardiac output. For this, RV O 2 consumption (MVO 2 ) …
Iron deficiency in systemic sclerosis patients with and without pulmonary hypertension
G Ruiter, IJ Lanser, FS de Man… - …, 2014 - academic.oup.com
Objectives. SSc-associated pulmonary hypertension (SSc-PH) has a worse prognosis compared
with SSc without PH (SSc-nonPH). Iron deficiency (ID) was previously associated with …
with SSc without PH (SSc-nonPH). Iron deficiency (ID) was previously associated with …
[HTML][HTML] Malnutrition in pulmonary arterial hypertension: a possible role for dietary intervention
CT Kwant, G Ruiter… - Current opinion in …, 2019 - journals.lww.com
Pulmonary arterial hypertension (PAH) is a lung disease characterized by increased blood
pressure (BP) in the pulmonary circulation ultimately causing right ventricular (RV) failure (…
pressure (BP) in the pulmonary circulation ultimately causing right ventricular (RV) failure (…