User profiles for G. G. Chen

GG chen

The Chinese university of Hong Kong
Verified email at cuhk.edu.hk
Cited by 60850

Estrogen and its receptors in cancer

GG Chen, Q Zeng, GMK Tse - Medicinal research reviews, 2008 - Wiley Online Library
The involvement of estrogen and its receptors in the development of cancer has been
known for years. However, the exact mechanism responsible is far from clear. The estrogen‐…

New insights into sorafenib resistance in hepatocellular carcinoma: Responsible mechanisms and promising strategies

…, L Liu, S Yang, J Ren, PBS Lai, GG Chen - Biochimica et Biophysica …, 2017 - Elsevier
It is disappointing that only a few patients with hepatocellular carcinoma (HCC) obtain a
significant survival benefit from the sorafenib treatment, which is currently regarded as a first-line …

Regulation of cell growth by estrogen signaling and potential targets in thyroid cancer

GG Chen, AC Vlantis, Q Zeng… - Current Cancer Drug …, 2008 - ingentaconnect.com
Thyroid cancer occurs three times more frequently in females than in males, and in females
the incidence decreases after menopause. This gender difference suggests that the growth …

Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

SG Torres-Platas, C Cruceanu, GG Chen… - Brain, behavior, and …, 2014 - Elsevier
Despite increasing evidence supporting the neuroinflammatory theory of depression, little is
known about cerebral macrophages in individuals suffering from major depression. In the …

[HTML][HTML] FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer

…, LZ Liu, IYP Wan, T Mok, MJ Underwood, GG Chen - Molecular cancer, 2017 - Springer
Background The role of cancer cell FOXP3 in tumorigenesis is conflicting. We aimed to study
FOXP3 expression and regulation, function and clinical implication in human non-small cell …

Shear force induced monodisperse droplet formation in a microfluidic device by controlling wetting properties

JH Xu, GS Luo, SW Li, GG Chen - Lab on a Chip, 2006 - pubs.rsc.org
Perpendicular flow is used to induce oil droplet breakup by using a capillary as water phase
flow channel. It is a new route to produce monodisperse emulsions. The wetting properties …

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

…, C Lui, C Zaelzer, EV Jones, BP Bally, GG Chen… - Science, 2016 - science.org
Astrocytes are specialized and heterogeneous cells that contribute to central nervous system
function and homeostasis. However, the mechanisms that create and maintain differences …

[HTML][HTML] An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

…, R Goodacre, NJ Turner, C Goble, GG Chen… - Communications …, 2018 - nature.com
The microbial production of fine chemicals provides a promising biosustainable manufacturing
solution that has led to the successful production of a growing catalog of natural products …

Oestrogen mediates the growth of human thyroid carcinoma cells via an oestrogen receptor–ERK pathway

Q Zeng, GG Chen, AC Vlantis… - Cell …, 2007 - Wiley Online Library
Objectives: Although thyroid cancer occurs much more frequently in females, the role of sex
hormones in thyroid carcinogenesis is unknown. In this study, it has been investigated how …

Isolation of the oleaginous yeasts from the soil and studies of their lipid-producing capacities

LX Pan, DF Yang, L Shao, W Li, GG Chen… - Food technology and …, 2009 - hrcak.srce.hr
D-xylose is one of the most abundant pentose sugars in nature. To isolate oleaginous yeasts
that can utilize xylose from diverse soil samples, soils from a litchi orchard, longan orchard, …