Kidney transplantation is the treatment of choice for patients with ESRD. Despite improvements
in short-term patient and graft outcomes, there has been no major improvement in long-…

… All patients received MMF 1.0 g twice daily (total dose 2.0 g), the initial dose being no later
than 48 hr after surgery. MMF therapy was continued for up to 6 months, after which the MMF …

In previous papers we demonstrated that cyclosporin A (C5A) was specifically oxidized in
rabbit and human liver by cytochrome P-450111A. We therefore anticipated that any drug that …

Although cold ischemia time has been widely studied in renal transplantation area, there is
no consensus on its precise relationship with the transplantation outcomes. To study this, we …

Atypical hemolytic and uremic syndrome (aHUS) is a severe disease strongly associated with
genetic abnormalities in the complement alternative pathway. In renal posttransplantation, …

The rabbit antithymocyte globulin T hymoglobulin first became available over 25 yr ago and
is the most widely used lymphocyte‐depleting preparation in solid organ transplantation. …

… Subsequent MMF dosing was 2 g/day on days 1 to 14 and then 1 g/day on days 15 to 183.
Up to 500 mg methylprednisolone or equivalent was administered as a single intravenous …

… dose of 2 g/d during months 1 and 2. Thereafter, the MMF dose could subsequently be
reduced to 1.5 g/d during month 3 and to 1 g/d thereafter according to individual center practices. …

Mycophenolate mofetil (MMF) has conventionally been administered at a fixed dose without
routinely monitoring blood levels of mycophenolic acid (MPA), the active metabolite. The …

This multicenter, 1:1-randomized, parallel-group, noninferiority study compared the efficacy
and safety of twice-daily tacrolimus (Tacrolimus BID; Prograf) and once-daily tacrolimus …